This book details the histologic clues in diagnosing the inflammatory dermatoses and neoplastic process of the vulva. The inflammatory dermatoses are divided into histologic patterns to aid recognition. Expert authors provide updates on ancillary techniques such as special stains, immunohistochemistry and chromogenic in situ hybridization when applicable. New advances in classifying squamous lesions as well as staging melanocytic lesions are outlined. They include the recent CAP/ASCCP (College of American Pathologists and the American Society for Colposcopy and Cervical Pathology) lower anogenital squamous terminology for HPV-associated lesions and the 2009 AJCC (American Joint Committee on Cancer) staging system for melanoma. New advances in molecular findings and potential targeted therapy are discussed for the squamous, melanocytic, adnexal and soft tissue tumors whenever it is pertinent. Vulvar Pathology will be a useful diagnostic guide for general pathologists, pathology trainees, dermatopathologists, dermatologists, and gynecologic pathologists in rendering diagnoses in vulvar inflammatory dermatoses as well as melanocytic, squamous, adnexal, and soft tissue neoplasms of the vulva.
Tabella dei contenuti
Part I: The Normal Vulva.- Normal Vulva: Embryology, Anatomy and Histology.- Part II: Inflammatory Dermatoses of the Vulva.- Histologic Clues in Interpreting Vulvar Inflammatory and Autoimmune Dermatoses.- Inflammatory Disorders Affecting the Epidermis of the Vulva.- Blistering Disorders and Acantholytic Processes Affecting the Epidermis of the Vulva.- Inflammatory Dermatoses Affecting the Dermis or Both the Epidermis and Dermis of the Vulva.- 6: Infectious Diseases and Infestations of the Vulva.- Part III: Melanocytic and Squamous Proliferations of the Vulva.- Pigmentary Alterations and Benign Melanocytic Lesions of the Vulva.- Malignant Melanoma of the Vulva.- Part IV: Vulvar Intraepithelial Neoplasia and Squamous Cell Carcinoma.- Squamous Intraepithelial Lesions of the Vulva.- Squamous Cell Carcinoma of the Vulva.- Part V: Cysts, Glandular Lesions, and Anogenital Mammary-Like Lesions of the Vulva.- Lesions of Anogenital Mammary-Like Glands, Adnexal Neoplasms, and Metastases.- Cysts, Glandular Lesions and Others.- Part VI: Mesenchymal Proliferations of the Vulva.- Fibrous/Myofibroblastic Proliferations of the Vulva.-Vascular Lesions of the Vulva.- Tumors of Smooth Muscle, of Skeletal Muscle, and of Unknown Origin and Tumor-Like Conditions of the Vulva.
Circa l’autore
Mai P. Hoang, MD
Harvard Medical School
Massachusetts General Hospital
Department of Pathology
Boston, MA
USA
Maria Angelica Selim, MD
Duke University Medical Center
Department of Pathology
Durham, NC
USA
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