The combination of two leading imaging techniques – magnetic resonance imaging and positron emission tomography – is poised to have a large impact and has recently been a driver of research and clinical applications. The hybrid instrument is capable of acquiring both datasets simultaneously and this affords a number of advantages ranging from the obvious, two datasets acquired in the time required for one, through to novel applications. This book describes the basics of MRI and PET and then the technical issues and advantages involved in bringing together the two techniques. Novel applications in preclinical settings, human imaging and tracers are described.
The book is for students and scientists entering the field of MR–PET with an MRI background but lacking PET or vice versa. It provides practical details from experts working in the area.
Tabella dei contenuti
Part A – Basics: Section I: Magnetic Resonance Imaging: Introduction to MRI; MRI Instrumentation; Selective Applications of MRI for Brain Imaging; Ultra-High Field and Emerging Applications; Section II: Positron Emission Tomography: Introduction to PET; Positron Emission Tomography Instrumentation; PET Quantification; Kinetic Modeling and Extraction of Metabolic Parameters; Part B – Hybrid MR-PET Imaging: Technical Overview: Section I: Hardware: Introduction and Historical Overview; MR-PET Instrumentation; Section II: Special Aspects of Data Corrections in MR-PET: MR-based Corrections for Quantitative PET Image; Motion Correction in Brain MR-PET; Section III: Special Considerations in MR-PET: MR-PET Measurement; Parametric Imaging; Technical and Methodological Aspects of Whole-body MR-PET; Part C – Human MR-PET Applications: Brain; Clinical Applications of Whole-body MR-PET; Part D – Preclinical Applications: Preclinical Hybrid MR-PET Scanner Hardware; Preclinical Applications of MR-PET; Part E – Tracers: Radiotracers for PET and MR-PET Imaging
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