Gene therapy as a potential method for the treatment of genetic disorders and other malignancies, as well as the treatment of many cancers, has attracted a great amount of attention in recent years. Current research focuses on stable and smart drug/gene-delivery systems, including controlled release. Nanoparticle (NP)-Based Delivery Vehicles looks at smart nanostructures and how these are considered a promising approach when applied to drug- and gene-delivery systems, in addition to how to solve the problems related to the inefficient transfer of medication to the affected cells.
Tabella dei contenuti
Contents
Chapter 1
An introduction to Drug/Gene Delivery Systems
Chapter 2
Smart nanostructures
Controlled gene delivery system: The concept
Chapter 3
Aptamer-based nanostructures
Aptamer-conjugated nanoparticles
Chapter 4
Protein-based nanostructures I
Gelatin
Gelatin synthesis approaches
Gelatin based nanocarriers
Chapter 5
Protein-based nanostructures II
Elastin
Elastin synthesis approaches
Elastin based nanocarriers
Chapter 6
Protein-based nanostructures III
Silk synthesis approaches
Silk based nanocarriers
Chapter 7
Strategic approach: toward the futures
Circa l’autore
Navid Rabiee graduated with an MSc in inorganic chemistry from Shahid Beheshti University, Iran, in 2018. He has also worked on drug-delivery systems based on biocompatible and biodegradable polymers associated with different types of the sensitizers, especially porphyrins, under the supervision of Mohammad Rabiee at Amirkabir University of Technology, in Iran. Mahsa Kiani graduated with an MSc in inorganic chemistry from Isfahan University of Technology, Iran, in 2015. In 2019, she joined ANNRG to collaborate with Mahdi Karimi’s research lab at Iran University of Medical Science, in Iran. Mojtaba Bagherzadeh is a professor at the Department of Chemistry of Sharif University of Technology, Iran. His current research interests include inorganic chemistry, inorganic catalysis and bio-inorganic chemistry. Mohammad Rabiee is an associate professor at the Biomedical Engineering Department of Amirkabir University of Technology, Iran. His current research interests include smart drug-delivery systems, tissue engineering and biological sensors. Spideh Ahmadi received her BSc in biology from Lorestan University, in 2011, and her MSc in molecular genetics from Zabol University, Iran, in 2014. She is currently working on smart nanostructures applied in therapeutic agent delivery systems employed for the diagnosis and therapy of various diseases.
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