Electrogenerated chemiluminescence (ECL) is a powerful and versatile analytical technique, which is widely applied for biosensing and successfully commercialized in the healthcare diagnostic market. After introducing the fundamental concepts, this book will highlight the recent analytical applications with a special focus on immunoassays, genotoxicity, imaging, DNA and enzymatic assays. The topic is clearly at the frontier between several scientific domains involving analytical chemistry, electrochemistry, photochemistry, materials science, nanoscience and biology. This book is ideal for graduate students, academics and researchers in industry looking for a comprehensive guide to the different aspects of electrogenerated chemiluminescence.
Tabella dei contenuti
Introduction and Overview of Electrogenerated Chemiluminescence; Energetic and Kinetic Aspects of ECL Generation; Efficient ECL Luminophores; Electrochemiluminescence Coreactants; Theoretical Concepts Underlying ECL Generation; The Essential Role of Electrode Materials in ECL Applications; Wireless ECL Generation Based on Bipolar Electrochemistry; Multicolour Electrochemiluminescence; ECL of Nanomaterials: Novel Materials, Detection Strategies and Applications; ECL Detection of Nanoparticles; Single Entity Electrogenerated Chemiluminescence; Enzymatic Assays; DNA-based ECL Assays; Microfluidic ECL and Voltammetric Arrays for Metabolite-related DNA Damage; Automated Immunoassays for the Detection of Biomarkers in Body Fluids; Electrochemiluminescence Imaging