Rafael A. (Dept. of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA) Irizarry & Michael I. (Dept. of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA) Love 
Data Analysis for the Life Sciences with R [PDF ebook] 

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.