Reviews our current understanding of the role of protein
oxidation in aging and age-related diseases
Protein oxidation is at the core of the aging process. Setting
forth a variety of new methods and approaches, this book helps
researchers conveniently by exploring the aging process and
developing more effective therapies to prevent or treat age-related
diseases. There have been many studies dedicated to the
relationship between protein oxidation and age-related pathology;
now it is possible for researchers and readers to learn new
techniques as utilizing protein oxidation products as biomarkers
for aging.
Protein Oxidation and Aging begins with a description of
the tremendous variety of protein oxidation products. Furthermore,
it covers:
* Major aspects of the protein oxidation process
* Cellular mechanisms for managing oxidized proteins
* Role of protein oxidation in aging
* Influence of genetic and environmental factors on protein
oxidation
* Measuring protein oxidation in the aging process
* Protein oxidation in age-related diseases
References at the end of each chapter serve as a gateway to the
growing body of original research studies and reviews in the
field.
Circa l’autore
TILMAN GRUNE, MD, is Full Professor and Director of the
Institute of Nutrition at Friedrich Schiller University Jena. His
research examines the biological phenomenon of oxidative stress. In
particular, his research group has been investigating the oxidative
stress response of cells and organisms and the protective influence
of antioxidants.
BETUL CATALGOL, MD, is Assistant Professor in the Faculty
of Medicine and the Department of Biochemistry at Marmara
University. She is coauthor of Proteasome and Neurodegenerative
Diseases, Proteasome and Cancer, and Protein Carbonyl
Measurement by Enzyme-Linked Immunosorbent Assay.
TOBIAS JUNG, Ph D, is a Research Assistant at Friedrich
Schiller University Jena. He is coauthor of Structure of the
Proteasome.
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