Yuzhuo Wang & Dong Lin 
Patient-Derived Xenograft Models of Human Cancer [PDF ebook] 

Supporto


This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text. 

Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the currentstatus of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field.

€96.29
Modalità di pagamento

Tabella dei contenuti

Introduction.- History and Evolution of PDX Cancer Models.- Establishment and Characterization of PDX Models.- Methods of Generating PDX Models.- Fidelity and Stability of PDX Models.- Applications of PDX Models.- Studies of Cancer Heterogeneity.- PDX and Cancer Stem Cells.- Modeling Cancer Metastasis.- Modeling Drug Resistance.- PDX and Biomarker Development.- PDX and Preclinical Drug Screening.- Co-clinical Trials and Personalized Cancer Therapy/Precision Medicine.- Epilogue.- Future Perspective.

Circa l’autore


Yuzhuo Wang, Ph D

Director, Living Tumor Laboratory

Distinguished Scientist, BC Cancer Agency

Senior Scientist, Vancouver Prostate Centre

Professor, University of British Columbia

675 West 10th Avenue, Room 3.122

Vancouver, BC, Canada V5Z 1L3

Dong Lin, Ph D, MD

Research Pathologist, Living Tumor Laboratory


Peter W. Gout, Ph D

Scientific Consultant, Living Tumor Laboratory

Honorary Associate Professor, Department of Urologic Sciences, University of British Columbia

Emeritus Senior Scientist, Department of Experimental Therapeutics, BC Cancer Agency
<675 West 10th Avenue, Room 5.108
Vancouver, BC, Canada V5Z 1L3


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Lingua Inglese ● Formato PDF ● Pagine 204 ● ISBN 9783319558257 ● Dimensione 6.5 MB ● Editore Yuzhuo Wang & Dong Lin ● Casa editrice Springer International Publishing ● Città Cham ● Paese CH ● Pubblicato 2017 ● Scaricabile 24 mesi ● Moneta EUR ● ID 5075242 ● Protezione dalla copia DRM sociale

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