An insightful exploration of the key aspects concerning the
chemical analysis of antibiotic residues in food
The presence of excess residues from frequent antibiotic use in
animals is not only illegal, but can pose serious health risks by
contaminating products for human consumption such as meat and milk.
Chemical Analysis of Antibiotic Residues in Food is a
single-source reference for readers interested in the development
of analytical methods for analyzing antibiotic residues in food. It
covers themes that include quality assurance and quality control,
antibiotic chemical properties, pharmacokinetics, metabolism,
distribution, food safety regulations, and chemical analysis. In
addition, the material presented includes background information
valuable for understanding the choice of marker residue and target
animal tissue to use for regulatory analysis. This comprehensive
reference:
* Includes topics on general issues related to screening and
confirmatory methods
* Presents updated information on food safety regulation based on
routine screening and confirmatory methods, especially LC-MS
* Provides general guidance for method development, validation,
and estimation of measurement uncertainty
Chemical Analysis of Antibiotic Residues in Food is
written and organized with a balance between practical use and
theory to provide laboratories with a solid and reliable reference
on antibiotic residue analysis. Thorough coverage elicits the
latest scientific findings to assist the ongoing efforts toward
refining analytical methods for producing safe foods of animal
origin.
About the author
JIAN WANG is currently a research scientist leading a
research and development unit for the Canadian Food Inspection
Agency in Calgary, Alberta. His responsibilities include planning
and conducting research projects in method development for
antibiotic and pesticide residues in foods using advanced mass
spectral analysis techniques such as UPLC/Q-TOF and LC/ESI-MS/MS.
He has written over thirty publications for various journals and
books. He was most recently awarded the CFIA Science Branch
Recognition Award for leading method development on melamine
investigation in 2007.
JAMES D. Mac NEIL retired as head of the Centre for
Veterinary Drug Residues of the Canadian Food Inspection Agency in
2007. His recent achievements include receiving the Joint FAO/WHO
Expert Committee on Food Additives 50th Anniversary commemorative
silver medal awarded in 2006 for services to JECFA; the Public
Service of Canada Award of Excellence, a career achievement in
2007; and appointment as scientist emeritus by CFIA in 2008. He is
the former scientific editor for ‘Drugs, Cosmetics, and Forensics’
of the Journal of AOAC International and the author of
numerous publications on veterinary drug residue analysis. He is
currently an adjunct professor in the Department of Chemistry,
Saint Mary’s University, Halifax, Canada.
JACK F. KAY works in the UK Department for Environment,
Food and Rural Affairs. He helped draft European Commission
Decision 2002/657/EC and, in 2008, introduced joint auditing to
this and ISO 17025 standards into a major UK laboratory. He has
actively participated in the Codex Committee on Residues of
Veterinary Drugs in Food for more than ten years and was appointed
an expert advisor on honey to the Food and Agriculture Organization
of the United Nations in 2008. Since 2005, he has held an Honorary
Senior Research Fellowship in the Department of Mathematics and
Statistics at the University of Strathclyde, Scotland.
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