This practical, well-organized reference delves deeply into
functional group transformations, to provide all the detailed
information that researchers need.
* Topics are organized into the following sections: oxidation,
reduction, asymmetric synthesis, and functional group
manipulations
* Each section includes a description of the functional group
transformation, the historical perspective, mechanisms, variations
and improvements on the reaction, synthetic utilities and
applications for the reaction, experimental details, and references
to the primary literature
* Contributors are well-known and respected for their work on the
specific name reactions.
Table of Content
Foreword vii
Preface viii
Contributing Authors ix
Chapter 1. Asymmetric Synthesis 1
Chapter 2. Reduction 85
Chapter 3. Oxidation 159
Chapter 4. Olefination 333
Chapter 5. Amine Synthesis 423
Chapter 6. Carboxylic Acid Derivatives Synthesis 457
Chapter 7. Miscellaneous Functional Group Manipulations 551
Appendixes 697
Appendix 1. Table of Contents for Volume 1: Name Reactions in Heterocyclic Chemistry 697
Appendix 2. Table of Contents for Volume 3: Name Reactions for Chain Extension 700
Appendix 3. Table of Contents for Volume 4: Name Reactions for Ring Formation 703
Appendix 4. Table of Contents for Volume 5: Name Reactions in Heterocyclic Chemistry-2 705
Subject Index 709
About the author
Jie Jack Li is a medicinal chemist at Pfizer Global Research
and Development in Ann Arbor, Michigan. He is coauthor of
Contemporary Drug Synthesis and editor of Name Reactions
in Heterocyclic Chemistry (both from Wiley).
E. J. Corey, Professor Emeritus at Harvard University, is
scientific editorial advisor for this book. Dr. Corey won the Nobel
Prize in Chemistry in 1990 for his development of the theory and
methodology of organic synthesis, and was awarded the Priestley
Medal in 2004.
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