Michael Wink 
Annual Plant Reviews, Volume 39, Functions and Biotechnology of Plant Secondary Metabolites [PDF ebook] 

This brand new Annual Plant Reviews volume is the second edition of
the highly successful and well-received Functions of Plant
Secondary Metabolites and their Exploitation in Biotechnology
(Annual Plant Reviews, Volume 3).

This exciting new volume provides an up-to-date survey of the
functions of plant secondary metabolites, their modes of action and
their use in pharmacology as molecular probes, in medicine as
therapeutic agents, and in agriculture as biorational pesticides.
The possibilities to produce valuable natural products in plant
cell and tissue culture and even in recombinant microorganisms are
also reviewed.

This carefully compiled new edition brings together chapters
from some of the world’s leading experts in plant secondary
metabolites. Completely revised and brought right up to date with
much new information, this volume is an essential purchase for
advanced students, researchers and professionals in biochemistry,
physiology, molecular biology, genetics, plant sciences,
agriculture, medicine, pharmacology and pharmacy, working in the
academic and industrial sectors, including those working in the
pesticide and pharmaceutical industries. Libraries in all
universities and research establishments where these subjects are
studied and taught will need copies of this excellent volume on
their shelves.

* A companion volume Annual Plant Reviews Volume
40, Biochemistryof Plant Secondary
Metabolism, Second Edition, Edited by M. Wink, is also
available.

Table of Content

List of contributors

Preface

1 Introduction

Michael Wink

1.1 Ecological function of secondary metabolites

1.2 Presence of defence and signal compounds at the right time
and place

1.3 Molecular modes of action of SM

1.4 Biotechnology and utilization of SM

1.5 Conclusions

2 Molecular Modes of Action of Defensive Secondary
Metabolites

Michael Wink and Oskar Schimmer

2.1 Introduction

2.2 Molecular modes of action – an overview

2.3 Accumulation of defence and signal compounds in plants

2.4 Animal responses: detoxification mechanisms and
adaptations

2.5 Concluding remarks

3 Chemical Defence in Marine Ecosystems

Annika Putz and Peter Proksch

3.1 Introduction

3.2 Marine natural products in allelopathic interactions

3.3 Chemical defence against fouling

3.4 Chemical defences of marine invertebrates and algae against
consumers

3.5 Favoured allocation of defensive metabolites in vulnerable
and valuable parts of marine invertebrates and algae

3.6 The flexible response: stress-induced accumulation of
defence metabolites and activation of protoxins

3.7 Endosymbionts as sources for allelochemicals found in marine
invertebrates

3.8 Conclusions and outlook

4 Plant-Microbe Interactions and Secondary Metabolites
with Antibacterial, Antifungal and Antiviral Properties

Jürgen Reichling

4.1 Introduction

4.2 Phytoalexins

4.3 Antibacterial and antifungal agents of higher plants

4.4 Secondary metabolites from higher plants with antiviral
properties

4.5 Conclusions

5 New Medical Applications of Plant Secondary Metabolites

Jörg Heilmann

5.1 Introduction

5.2 Compounds with anticancer and chemopreventive activity

5.3 Antiviral compounds

5.4 Antimalarial drugs

5.5 Anti-inflammatory drugs

5.6 Antidepressant drugs

5.7 Anti-ischaemic drugs

5.8 Immunostimulatory drugs

5.9 Conclusions

6 Production of Natural Products by Plant Cell and Organ
Cultures

August-Wilhelm Alfermann

6.1 Introduction

6.2 Production of natural products by cell and organ
cultures

6.3 Elicitation

6.4 Increase/decrease of product yields by genetic
manipulation

6.5 Biosynthetic pathways delineation using RNA-interference

6.6 Mass cultivation of plant cell cultures

6.7 Production of recombinant proteins by plants and plant cell
cultures

6.8 Production of plant natural products in microbes

6.9 Perspectives

Index

About the author

Michael Wink is Professor of Pharmaceutical Biology and Director at the Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, Germany