This book gathers together the results of research on the Boolean domain related to important real-life applications that will support the reader in solving their scientific and practical tasks. It highlights that ongoing digitalization leads to increasing amounts of complex applications, the digits of which are usually encoded by Boolean variables due to their simplicity as only two values are used. However, as shown here, an exponentially growing number of vectors of Boolean variables can negate this simplicity, which leads to challenges in advancing progress in the Boolean domain and supporting a wide range of applications.