In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and Erb B2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. Breast Cancer Chemosensitivity provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.
Dihua Yu & Mien-Chie Hung
Breast Cancer Chemosensitivity [PDF ebook]
Breast Cancer Chemosensitivity [PDF ebook]
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Bahasa Inggeris ● Format PDF ● Halaman-halaman 175 ● ISBN 9780387740393 ● Saiz fail 1.8 MB ● Penyunting Dihua Yu & Mien-Chie Hung ● Penerbit Springer New York ● Bandar raya NY ● Negara US ● Diterbitkan 2009 ● Muat turun 24 bulan ● Mata wang EUR ● ID 2145857 ● Salin perlindungan Social DRM