This book emphasizes dose selection issues from a statistical point of view. It presentsstatisticalapplicationsinthedesignandanalysisofdose–responsestudies. The importance of this subject can be found from the International Conference on Harmonization (ICH) E4 Guidance document. Establishing the dose–response relationship is one of the most important act- ities in developing a new drug. A clinical development program for a new drug can be broadly divided into four phases – namely ...
Jadual kandungan
and New Drug Development Process.- Dose Finding Based on Preclinical Studies.- Dose-Finding Studies in Phase I and Estimation of Maximally Tolerated Dose.- Dose-Fin...
Beli ebook ini dan dapatkan 1 lagi PERCUMA!
Bahasa Inggeris ● Format PDF ● Halaman-halaman 248 ● ISBN 9780387337067 ● Saiz fail 3.8 MB ● Penyunting Naitee Ting ● Penerbit Springer New York ● Bandar raya NY ● Negara US ● Diterbitkan 2006 ● Muat turun 24 bulan ● Mata wang EUR ● ID 2144826 ● Salin perlindungan Social DRM