William E. Schiesser 
Spatiotemporal Modeling of Cancer Immunotherapy [PDF ebook] 
Partial Differential Equation Analysis in R

Sokongan

The focus of this book is a detailed discussion of a dual cancer vaccine (CV)-immune checkpoint inhibitor (ICI) mathematical model formulated as a system of partial differential equations (PDEs) defining the spatiotemporal distribution of cells and biochemicals during tumor growth.

A computer implementation of the model is discussed in detail for the quantitative evaluation of CV-ICI therapy. The coding (programming) consists of a series of routines in R, a quality, open-source scientific computing system that is readily available from the internet. The routines are based on the method of lines (MOL), a general PDE algorithm that can be executed on modest computers within the basic R system. The reader can download and use the routines to confirm the model solutions reported in the book, then experiment with the model by varying the parameters and modifying/extending the equations, and even studying alternative models with the PDE methodology demonstrated by the CV-ICI model.

Spatiotemporal Modeling of Cancer Immunotherapy: Partial Differential Equation Analysis in R facilitates the use of the model, and more generally, computer- based analysis of cancer immunotherapy mathematical models, as a step toward the development and quantitative evaluation of the immunotherapy approach to the treatment of cancer.

To download the R routines, please visit: http://www.lehigh.edu/~wes1/ci_download

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Jadual kandungan

Fixed Boundary PDE Model Formulation.- Fixed Boundary PDE Model Implementation.- Fixed Boundary PDE Model Output.- Moving Boundary PDE Model Implementation.- Moving Boundary PDE Model Output.- Index.

Mengenai Pengarang

William E. Schiesser is Emeritus Mc Cann Professor of Computational Biomedical Engineering, Biomolecular and Chemical Engineering, and Professor of Mathematics at Lehigh University.

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Bahasa Inggeris ● Format PDF ● Halaman-halaman 112 ● ISBN 9783030190804 ● Saiz fail 4.1 MB ● Penerbit Springer International Publishing ● Bandar raya Cham ● Negara CH ● Diterbitkan 2019 ● Muat turun 24 bulan ● Mata wang EUR ● ID 7028878 ● Salin perlindungan Social DRM

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