Regenerative medicine promises to be one of the great future frontiers. Critical to the success of this area is stem cell research, and cell- and gene-based therapy. In this book, a variety of outstanding authors discuss important aspects of these research areas. Important topics include new types of cell therapies and stem cell-based therapy for angiogenesis and cardiac repair. They also include cell-therapy approaches in neu- logic areas such as Parkinson’s disease, multiple sclerosis, and stroke. A third area that is explored involves the development of cell-based systems for cartilage and bone repair, bladder repair, and kidney regeneration. A fourth area involves important work in the eye, specifically, optic nerve regeneration, retinal repair, and ocular surface regene- tion. The potential of using insulin-producing cells or islets is also examined in this book, as are strategies for cord blood transplantation for various hematologic disorders. Finally, important areas of research involving skin regeneration and wound healing are discussed. This book should provide an excellent overview of the important areas in regenerative medicine with respect to cell and gene therapy and hopefully will be a u- ful guide for scientists doing research in these areas.
Inhoudsopgave
Heart.- Renovation of the Injured Heart with Myocardial Tissue Engineering.- Adult Stem Cells for Myocardial Tissue Repair.- Regeneration of the Functional Myocardium Using Human Embryonic Stem Cells.- Therapeutic Angiogenesis.- Cell Therapy for Heart Failure.- Neuro.- Cell Transplantation for Diseases of Myelin.- Stem Cells as a Source for Cell Replacement in Parkinson’s Disease.- Cell Replacement Therapy in Acute Stroke: Current State.- Gene Therapy to the Nervous System.- Musculoskeletal.- Mesenchymal Stem Cells: Where Can You Find Them? How Can You Use Them?.- Basic to Clinical Cartilage Engineering: Past, Present, and Future Discussions.- Cartilage.- Bone Regeneration.- Osteoarthritis and Mesenchymal Cells — The Prospects for Repair of the Disease by Cell Transplantation and Tissue Engineering.- Kidney.- Progenitor Cell Therapy for Kidney Regeneration.- Tissue Engineering — The Bladder.- Eye.- Neuroprotection in Ophthalmology: A Review.- Autoimmunity for Central Nervous System Maintenance, Regeneration, and Renewal: Development of a T Cell-Based Vaccination Against Neurodegeneration.- Retinal Repair by Stem Cell Transplantation.- Induction of Ocular Surface Regeneration.- Pancreas.- Insulin-Producing Cells Generated from Nonpancreatic Tissues.- Generation of Islets from Pancreatic Progenitor Cells.- Embryonic Stem Cells as a Source of Pancreatic Precursors and Islet Cells in Vitro.- Hematology.- Human Umbilical Cord Blood Transplantation: A Viable Option for Stem Cell Graft.- Nonmyeloablative Stem Cell Transplantation in the Treatment of Hematologic Malignancies.- Hematopoietic Stem Cell Transplantation from Human Leukocyte Antigen Haploidentical Donor.- Skin.- Wound Healing and Skin Substitutes.- Skin Regeneration from Multipotent Adult and Embryonic Stem Cells.
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