Clinical Hepatology – Principles and Practice of Hepatobiliary Diseases provides clear and comprehensive coverage of the etiology, mechanisms of disease, diagnosis, and practical management of the entire spectrum of liver and biliary disorders. It also affords an excellent, evidence-based review of the rapidly expanding field of hepatobiliary diseases.
Inhoudsopgave
Structure and Function of the Liver.- Embryonic Development.- Gross Anatomy.- Microscopic Anatomy.- Hepatic Circulation.- Hepatocellular Transport.- Hepatic Metabolism.- Formation and Secretion of Bile and Bilirubin Metabolism.- Hepatic Biotransformation.- Functional Heterogeneity and Metabolic Zonation.- Liver Cell Hydration and Cell Function.- The Liver as an Immune Organ.- Aging and the Liver.- Hepatic Regeneration.- Pathophysiology and Morphology of Liver Injury.- Free Radicals, Reactive Oxygen Species, Oxidative and Endoplasmic Reticulum Stress.- Hypoxic Liver Injury.- Reperfusion Injury.- Drug-Induced and Toxic Liver Injury.- Immune Mediated Liver Injury.- Endotoxin Mediated Liver Injury.- Cholestasis-Induced Liver Injury.- Metal-Induced Liver Injury.- Radiation-Induced Liver Damage.- Liver Cell Degeneration and Cell Death.- Cellular Adaptation, Intracellular Inclusions and Deposits.- Necroinflammatory Reaction.- Cholestatic Reaction.- Granulomatous Reaction.- Fibrogenic Reaction.- Histopathological Scoring Systems.- Clinical Scoring Systems.- Evaluation of the Patient with Hepatobiliary Disease.- History.- Symptoms.- Physical Examination.- Basic Laboratory Parameters.- Tests of Liver Function.- Autoantibodies.- Ultrasonography.- Computed Tomography and Magnetic Resonance Imaging.- Nuclear Imaging.- Endoscopic Retrograde and Percutaneous Transhepatic Cholangiography.- Cholangioscopy.- Endoscopic Ultrasonography.- Percutaneous Liver Biopsy.- Transvenous Liver Biopsy.- Laparoscopy.- Measurement of Portal Pressure.- Sphincter of Oddi Manometry.- Approach to the Patient with Upper Abdominal Pain.- Approach to the Patient with Abnormal Liver Enzymes.- Approach to the Patient with Hepatomegaly.- Approach to the Patient with Focal Liver Lesions.- Approach to the Patientwith Cholestasis and Jaundice.- Approach to the Patient with Portal Hypertension.- Approach to the Patient with Ascites.
Over de auteur
Henryk Dancygier is Chief of the Department of Medicine II at the Klinikum Offenbach, and Professor of Medicine at the Goethe University, Frankfurt/Main. He graduated from the University of Heidelberg and trained in Pathology, Internal Medicine, Gastroenterology and Hepatology. He holds degrees from the University of Heidelberg, Frankfurt and the Technical University of Munich and currently is Adjunct Professor of Medicine at the Mount Sinai School of Medicine, New York.
Henryk Dancygier is author of a number of books including (English translations) ‘AIDS – a Clinical Compendium’ (1993), ‘Memorix – Gastroenterology and Hepatology’ (1998), ‘Endosonography in Gastroenterology: Principles, Techniques, Findings’ (1999), ‘Liver Diseases – the ABC of Therapy’ (2003) and ‘Clinical Hepatology – Diagnosis and Therapy of Hepatobiliary Disorders’ (2003) that have been translated into several languages and he has also contributed numerous chapters in Medical Textbooks.
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