Edited by a leading authority in the field, the first book on this important and emerging topic provides an overview of the latest trends in sequence-controlled polymers.
Following a brief introduction, the book goes on to discuss various synthetic approaches to sequence-controlled polymers, including template polymerization, genetic engineering and solid-phase chemistry. Moreover, monomer sequence regulation in classical polymerization techniques such as step-growth polymerization, living ionic polymerizations and controlled radical polymerizations are explained, before concluding with a look at the future for sequence-controlled polymers.
With its unique coverage of this interdisciplinary field, the text will prove invaluable to polymer and environmental chemists, as well as biochemists and bioengineers.
Inhoudsopgave
Introduction to Sequence-Controlled Polymers
Chemical Synthesis of Genetic Polymers
Synthesis of Sequence-Controlled Polymers by Genetic Engineering
Synthesis of Peptide-Polymer Bio-Hybrids
Synthesis of Peptidomimetics and Peptoids
Iterative Synthesis of Non-Natural Polymers
Synthesis of Sequence-Defined Foldamers
Folding of Sequence-Defined Polymers into Single-Chain Nanoparticles
Sequence-Control in Chain-Growth Ionic Polymerizations
Sequence-Control in Chain-Growth Radical Polymerizations
Sequence-Control in Step-Growth Polymerizations
Synthesis of Multiblock Copolymers
Properties of Sequence-Controlled Polymers
Sequencing of Non-Natural Polymers
Over de auteur
Dr. Jean-François Lutz is CNRS research director, deputy director of the Institut Charles Sadron and head of the Precision Macromolecular Chemistry group in Strasbourg, France. He obtained his Ph D from the University of Montpellier II, France, in 2000 and his habilitation degree from the University of Potsdam, Germany, in 2009. Before joining the CNRS, he subsequently was a post-doctoral fellow in the group of Krzysztof Matyjaszewski at Carnegie Mellon University, USA (2001-2003) and group leader Nanotechnology for Life Science at the Fraunhofer Institute for Applied Polymer Research in Potsdam (2003-2010).
He received in 2008 the prize of the polymer division of the French Chemical Society and he is listed since 2015 as an ISI Highly-Cited Researcher in Chemistry. He is also an European Research Council (ERC) laureate since 2010 through successive starting (St G 2010) and proofs of concept (Po C 2015) grants. His current research interests include the synthesis of sequence-controlled polymers, single-chain technologies and the preparation of information-containing macromolecules. He is author of more than 200 publications.
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