By covering topics from individual molecules to systemic diseases, from fundamental concepts to advanced technologies, this book intends to provide a practical, state-of-the-art, and integrative view of the application of pharmacogenomics indrug discovery and development.The second aspect composes a large part of this book: a focus on how pharmacogenomicscan be used in therapeutics of diseases. These diseases include cardiovascular diseases, cancer, neurological diseases, gastrointestinal disorders, autoimmune diseases, and infectious diseases. Comprehensive information for each diseasesystem is discussed, including biomarkers involved in the disease and the associations among genes, drugs, diseases, drugresponse phenotypes, and the environment.
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