Auteur: Ronco

During the past decade, experimental and clinical studies have suggested that dyslipidemia may be an important risk factor for the progression of renal disease. This volume explores in great detail r …

This volume of Contributions to Nephrology is comprised of papers presented at the 7th International Ammoniagenesis Workshop. The presentations are organized into sections dealing with ammonia-formin …

I would recommend this slim volume for geneticists with an interest in hereditary kidney diseases who would appreciate well written and referenced, up to date papers on the specific conditions includ …

The present volume is a reprint of a series of the lectures, first published in a special section of `Nephron’. It covers such diverse aspects of clinical nephrology as the cardiovascular system, tra …

This volume presents a unique compilation of reviews on cell volume regulation in health and disease, with contributions from leading experts in the field. The topics covered include mechanisms and s …

This book surveys experiences made with Polymethylmethacrylate (PMMA) dialysis membranes, ranging from a summary of the most recent experimental and clinical results to an overview of future potentia …

The author of this volume has studied Ig A nephropathy for nearly 25 years, almost as long as primary Ig A nephropathy has been recognized as a new disease. Ig A nephropathy, considered to be an immu …

In recent years, major concerns have been expressed about long-term derangements in hemodialysis patients and possible clinically relevant blood-membrane interactions. Preliminary studies employing b …

Cancer is above all a heritable disorder of somatic cells and gene expression, but environment is also involved in its origin. Hereditary kidney cancer should prove valuable to understand the mechani …

While continuous ambulatory peritoneal dialysis (CAPD) has been the standard peritoneal procedure since the seventies, different schedules of automated peritoneal dialysis (APD) have emerged during t …

There is considerable evidence suggesting that chronic cigarette smoking has adverse health effects: it is the major cause of disease and death in developed countries, inducing several kinds of cance …

The pathological role of advanced glycation end products (AGEs) and of oxidative-carbonylic stress is well known in the context of diabetes. Moreover, there is also strong evidence that they play a p …

In the last twenty years, critical care medicine has been established as a specialty with its own therapies and procedures, with significant implications for clinical nephrology regarding severe acut …

Over the last decade, the availability of new devices and membranes has led to the development of modern hemodialysis techniques in which clinical tolerance and efficiency have significantly improved …

Type-2 diabetic nephropathy is one of the major long-term microvascular complications occurring in nearly 40% of diabetic patients in Japan. The purpose of this book is to review recent work on the g …

The renin-angiotensin system (RAS) has long been seen as a systemic endocrine system in which angiotensin II (ANG II) is solely involved in blood pressure regulation and the mediation of aldosterone …

Patients with rare disorders are often condemned to neglect: their disease is difficult to recognize, the information available on possible therapies is scanty (if there exists one at all) and, due t …

This publication is a collection of the papers presented at the ‘First International Course on Hemodialysis Technology’, Vicenza, June 2002: It covers a wide range of topics, including aspects of vas …

Since high-permeability membranes were first introduced, their performance has constantly improved. The publication at hand focuses on a new polymer, polyethersulfone, which was designed to provide b …

This publication provides a synopsis of the rapid progress made in the field of renal cell biology during the last decade, progress which has resulted in a better conceptual understanding of the cell …

Peritoneal dialysis (PD) is an invaluable tool in the treatment of patients with end-stage renal disease, which does not preclude a renal transplant, but incurs lower costs than other treatment optio …

The novel discipline of proteomics has experienced a rapid growth in the recent past and has a great potential for the future. Involving several fields, it offers various advantages: The study of pro …

Recent developments have spurred a renewed interest in novel solutions to access the patient circulation, mainly concentrating on vascular access for renal replacement therapies and on peritoneal dia …

Chronic kidney disease is one of the world’s major public health problems, and the prevalence of kidney failure is rising steadily. Among the risk factors for a faster progression of renal disease ar …

Severe sepsis is among the most common causes of death in the United States and the most common cause of death in the Intensive Care Units worldwide, and its recognition and treatment remain the most …

As the frequency of hemodialysis sessions has always been a concern, it is not astonishing that interest in quotidian (daily) hemodialysis appears to be growing worldwide. The main reasons for more f …

Transplantation is today firmly established as the therapy of choice for end-stage organ failure. However, despite recent developments, this therapy is still not without challenges and risks: The nec …

Uric acid disorders are involved in both nephrological and hematological diseases. One of these crystal-associated diseases which has been known since antiquity is gout. More recently, tumor Lysis sy …

Heat shock proteins are a distinctive class of proteins that have evolved to cope with stress and to provide cellular defense against a wide range of cell injuries. Cellular stress responses include …

Hemodialysis therapy has become a well-established form of renal replacement, and due to continuous improvements in technology, a series of new biomaterials and techniques for the clinical routine ha …

Even though peritoneal dialysis (PD) is by now well established and its advantages in terms of clinical efficacy, social impact and individual tolerance are acknowledged, it is still underutilized on …

We are currently facing an alarming obesity epidemic, with its well-known health consequences such as metabolic syndrome / type 2 diabetes, cardiovascular diseases, an increased incidence of certain …

It is essential for the survival of cells to maintain their volume within certain limits: Profound alterations interfere with the integrity of the cell membrane and the cytoskeletal architecture. Cel …

In recent years, the knowledge of how renal damage occurs in patients with plasma cell dyscrasias / myeloma has substantially increased. For the first time, this publication brings together issues re …

Sodium hypochlorite has long been recognized for its effectiveness as an antiseptic and disinfectant, but its practical use in medicine had been limited due to its reduced stability. However, it has …

It is well-known that the daily diet plays an important role in the preservation and integrity of renal function in patients with chronic kidney disease. However, there currently exists some confusio …

Acute kidney injury is defined as an abrupt change in serum creatinine and/or urine output, and a majority of patients admitted to the ICU have some evidence of the disorder. Unfortunately, treatment …

Primary Ig A nephropathy has first been described as a new disease entity almost 40 years ago. This disorder, considered to be an immune-complex-mediated glomerulonephritis, is characterized by granu …

The application of hemodiafiltration has been restricted until recently, when a broader clinical application has been made possible due to evidence from large studies and clinical investigations. Thi …

Despite the various advantages of home dialysis compared to in-center hemodialysis, only a fraction of patients in Japan currently opt for peritoneal dialysis or home hemodialysis. However, considera …

This publication contains the most recent findings in the field as presented by the outstanding faculty of the 2012 International Vicenza Course on Peritoneal Dialysis. After 30 years, this course is …

Chronic kidney disease (CKD) is an established risk factor for cardiovascular diseases. Stroke, on the other hand, is not only a major player in cardiovascular disease, but it also has strong two-way …

The enormous progress made during the last decade has resulted in a better conceptual understanding of mineral ion metabolism in general. With regard to chronic kidney disease, the two most affected …

Chronic kidney disease is a global major health issue that ultimately leads to end-stage renal disease, a devastating condition requiring costly renal replacement therapy. Given this background, exte …

Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This b …

The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of i …

Not only are dialysis access creation and maintenance prone to complications, but patients suffering from end-stage renal disease and its comorbidities generally have a high risk of adverse events du …

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The buttonhole method for the cannulation of the arteriovenous fistula was discovered more than 40 years ago and was soon adopted on a wide scale due to its obvious benefits of decreased puncture pai …

Acute kidney injury (AKI) is a serious disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions and exposures. It is very common in …

Ultrasound imaging techniques are an indispensable complement to physical examination, which is often frustrating, if not useless, for diagnosing kidney problems. The application of ultrasound techni …

This book brings together papers presented both during the 61st Annual Meeting of the Japanese Society for Dialysis Therapy (JSDT) and the 34th Congress of the International Society of Blood Purifica …

After years of stagnation, much has been happening in the diagnosis and treatment of kidney diseases. This book contains a comprehensive review of the main developments in AKI, CKD, hemodialysis and …

Despite constant significant advances, cardiovascular as well as more general outcomes of hemodialysis treatment remain unsatisfactory. The introduction of innovative ‘high retention onset’ membranes …

Hyperuricemia is often associated with life-style related disorders such as diabetes mellitus, hypertension, and dyslipidemia, which, in turn, are major causes of CKD. Improved management of hyperuri …

The number of dialysis patients, and their ages, continues to increase globally. This creates major issues such as rising medical costs in an aging population, how to best manage end-of-life care, an …

Continuous renal replacement therapies (CRRT) started off as an alternative to hemo- or peritoneal dialysis. Today’s machines and techniques are the result of 4 decades of developments, studies, and …

Acute Kidney Injury (AKI) is a complex syndrome that is prevalent among hospitalized patients. In recent years, occurrence of AKI events has risen due to a growing susceptibility of fragile and elder …

Chronic kidney disease (CKD) is a global health burden with associated high economic costs to the health system. Main factors are the increasing number of patients with diabetes and hypertension and …

Initially conceived as a strategy to remedy inherited genetic disorders, gene therapy has been successfully applied in the last decade to ameliorate the renal function compromised by progressive rena …

Since the publication of the first volume on proteomics in nephrology, methodologies and protocols for renal and urinary proteome analyses have been continuously improved, resulting in considerable p …

The field of hemodialysis is subject to constant transformations due to continuous advances in techniques, biomaterials and devices. Based on international surveys, objective evaluations of experts a …

As recent advances in immunosuppression and apheresis techniques have opened new avenues for the management of humoral immunity, interest in ABO-incompatible kidney transplantation has been renewed. …

The importance of peritoneal dialysis (PD) in the therapy of chronic kidney disease has been steadily increasing. The simultaneous advancement in clinical practice and basic research has increased ov …

Fluid overload is often observed in patients with heart failure and secondary oliguric states. A thorough assessment of the fluid status of the patient may help guide the therapy and prevent complica …

Critical care nephrology is an emerging multidisciplinary science in which the competences of different specialists are merged to provide a unified diagnostic and therapeutic approach to the critical …

Acute organ damage and the ensuing multiple organ failure are the result of a pathophysiological process involving various cytokines. Once activated, these proteins cannot be eliminated even when the …

The presence of endotoxin in the bloodstream is the consequence of an immunological response triggered by bacterial invasion of the host. This condition leads to altered cardiovascular function, lung …

Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this informat …

Hemodiafiltration (HDF) for the treatment of end-stage renal disease patients is predominantly performed in European countries and in Japan, with some differences in technique such as rate of blood f …

Caused by an epidemic increase in obesity and diabetes and metabolic syndromes, diabetic nephropathy has become a leading cause of end-stage renal disease in many developed countries. The publication …

This book contains notable contributions from the well-known Vicenza course on hemodialysis and miniaturized wearable devices for renal replacement therapy.The main themes covered in this publication …

Endothelin is a 21-amino acid peptide that exerts uniquely potent and long-lasting effects on the kidney, including regulation of water and electrolyte excretion, blood pressure, cell growth, inflamm …

Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. …

Dialyzers today are developed with high permeability and biocompatibility in mind, even though the definition of these so-called high-flux dialyzers remains controversial. In the Japanese reimburseme …

Hepatitis C virus (HCV) infection is a major health problem worldwide, with currently over 150 million HCV-infected people on the five continents. Although there have been important advances in the d …

On-line HDF represents a major technical development in the delivery of hemodialysis therapy: It combines the properties of increased diffusion available in current high-flux membranes with convectiv …

Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the d …