Collagen: Structure and Mechanics provides a cohesive introduction to this biological macromolecule and its many applications in biomaterials and tissue engineering.
Graduate students and postdoctoral researchers in the fields of materials, (bio-)engineering, physics, chemistry and biology will gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates, across all length scales from the molecular (nano) to the organ (macro) level. Written in a clear and didactic manner, this volume includes current knowledge on the hierarchical structure, mechanical properties, in addition to a review of deformation and strengthening mechanisms.
Collagen: Structure and Mechanics is an excellent reference for new researchers entering this area and serves as a basis for lecturing in the interdisciplinary field of biological materials science.
Table of Content
Collagen: Structure and Mechanics, an Introduction.- Collagen Diversity, Synthesis and Assembly.- Collagen Fibrillar Structure and Hierarchies.- Restraining Cross-Links Responsible for the Mechanical Properties of Collagen Fibers: Natural and Artificial.- Damage and Fatigue.- Viscoelasticity, Energy Storage and Transmission and Dissipation by Extracellular Matrices in Vertebrates.- Nanoscale Deformation Mechanisms in Collagen.- Hierarchical Nanomechanics of Collagen Fibrils: Atomistic and Molecular Modeling.- Mechanical Adaptation and Tissue Remodeling.- Tendons and Ligaments: Structure, Mechanical Behavior and Biological Function.- Collagen in Arterial Walls: Biomechanical Aspects.- The Extracellular Matrix of Skeletal and Cardiac Muscle.- The Cornea and Sclera.- Collagen and the Mechanical Properties of Bone and Calcified Cartilage.- Dentin.- Genetic Collagen Diseases: Influence of Collagen Mutations on Structure and Mechanical Behavior.- Biomimetic Collagen Tissues: Collagenous Tissue Engineering and Other Applications.
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