In Vivo Models of Inflammation (Vol. 1 and Vol. 2) provides the biomedical researcher in both the pharmaceutical industry and academia with a description of the state of the art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first edition by describing and updating the standard models that are most utilized for specific disease areas. In addition, new models are included exploring emerging areas of inflammation research.
Pioneering ideas and provocative comments about future directions are meant to challenge the status quo and stimulate new thinking. Therefore, new approaches to the development of future models in selected therapeutic areas have been highlighted. The focus on novel technologies that are vital for innovative in vivo research has been expanded to include chapters on the use of transgenic and gene transfer technologies, nanotechnology, and stem cells.
The aim of this set of books is to provide current best practices for obtaining the maximum information from in vivo experimentation, while preserving the dignity and comfort of the animal.
Spis treści
Asthma.- In vivo modeling systems for chronic obstructive pulmonary disease.- Murine models of allergen-induced airway hyperresponsiveness and inflammation.- Skin inflammatory disorders.- In vivo models of neurogenic inflammation.- Animal models of inflammatory bowel disease.- Preclinical models of vascular inflammation.
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