Atherosclerosis is a degenerative process affecting blood vessels, which determines narrowing of the lumen, plaque growth, and hardening of the walls. It is a risk factor for cardiovascular diseases. The focus of this book is on the management of the atherosclerotic disease. The coverage of this book spans from histological presentation of the various stages of atherosclerotic lesions to the earliest studies in atherosclerosis therapy, from advanced clinical diagnosis to monitoring, follow-up, and home-care of the atherosclerotic patient. The book shows well-established diagnostic techniques covering several medical imaging modalities such as Ultrasounds, IVUS, MRI, Computer Tomography, along with new trends in early and advanced atherosclerosis diagnosis (innovative drugs and tissue characterization procedures). Surgical standards will be presented along with innovative experimental trials for the treatment of the atherosclerotic patient. The book will also cover emerging techniques based on molecular imaging and vibro-acoustics.
Spis treści
Importance Atherosclerosis Imaging and Treatment.- Carotid pathologies: type, incidence, and therapy.- Cardiovascular risk in subjects with carotid pathologies.- Noninvasive cerebrovascular risk assessment in presence of carotid lesions.- Histology and its correlation with instrumental measure.- Issues and Challenges in Ultrasound Vascular .- Despeckle Filtering of Ultrasound .- Review on Plaque Characterization and Carotid Imaging.- Signal Processing Approach to 2-D longitudinal and transverse B-Mode Carotid Images.- Plaque morphology and reconstruction.- The use of ultrasound contrast agents in plaque characterization.- IVUS.- CCA Segmentation.- MRI imaging of carotid lesions.- Carotid Stenosis Estimation in X-rays.- Fusion Techniques for CCA.- MR carotid Segmentation using Gibbs Model.- MR Stenosis Analysis.- carotid plaques by noninvasive imaging.- MR Plaque Characterization.- CT- Atherosclerosis Imaging.- Hemodynamics.- FEM for Carotid and Stroke Analysis.- Surgical intervention: stenting vs endarterectomy.- Drug Therapy and follow-up.- Clinical management and follow-up of patients with carotid disease.- Vaccinia virus, protein and atherosclerotic lesions.- Nanoparticle Based Atherosclerosis Mgt.- In Vivo Vibroacoustography for Vascular Artery and Veins.- SDUV technique for measuring mechanical properties of Plaqued Arteries.- Metabolomics in patients with carotid artery diseases.- Lipid Management in CCA.- Molecular Imaging of Atherosclerosis.- Biologic Nanoparticles in Atherosclerosis Diseases.
O autorze
Dr. Jasjit Suri has spent over 20 years in biomedical engineering/sciences/devices and his last 14 years has been dedicated in the field of medical imaging modalities and its fusion. He has published more than 300 technical papers in body imaging and devices, relating to modalities like MR, CT, X-ray, Ultrasound, PET, SPECT, Elastography and Molecular Imaging. Dr. Chirinjeev Kathuria holds a Bachelor of Science (B.Sc.) degree and specialized in U.S. Health Care Policy and Administration and a Doctor of Medicine (M.D.) from Brown University. He also holds a Master’s in Business Administration (M.B.A.) from Stanford University. Dr. Filippo Molinari received the Italian Laurea and the Ph.D. in Electrical Engineering from the Politecnico di Torino, Torino, Italy, in 1997 and 2000, respectively. Since 2002, he has been an assistant professor on the faculty of the Department di Electronics, Politecnico di Torino, where he teaches biomedical signal processing, biomedical image processing, and instrumentation for medical imaging.
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