Over the past 2 decades, there has been a steady increase in knowledge associated with the clinical manifestations of cholestatic liver disease. In addition to a growing amount of information on the well-studied disorders of primary biliary cirrhosis and primary sclerosing cholangitis, there has been a rapid accumulation of data on less well-known but important topics such as overlap syndromes with autoimmune hepatitis, cholestatic variants of alcohol and viral disease, and cholestasis following liver transplantation. These emerging insights are complemented by further improvements of the diagnosis and management of cholestasis.
Based on these clinical situations, Cholestatic Liver Disease provides essential information for individuals involved in the care of patients affected by cholestatic liver disease. This groundbreaking text also supplies scientific updates from leading experts which relate to the clinical evaluation and management of cholestatic liver disorders, useful for both novice and practitioners alike. Among the topics discussed in this volume are PBC, PSC, overlap syndrome with autoimmune hepatits, sarcoid, lymphoma, cystic fibrosis, rheumatologic disease, and osteoporosis. Comprehensive and timely, Cholestatic Liver Disease is sure to be an indispensable reference for all those who work with cholestatic liver.
Spis treści
Diagnosis of cholestasis Liver tests/antibodies.- Drug-induced cholestasis Include herbal remedies.- PBC Usual (overlap and recurrence after transplant covered elsewhere).- PSC Usual (overlap and recurrence after transplant covered elsewhere) Risk of colon CA with IBD, colon CA post-transplant, and cholangiocarcinoma.- Overlap Syndrome with autoimmune hepatitis.- Rare causes of cholestasis (genetic disorders).- Cholestatic variants of alcohol, viral disease Alcohol Hepatitis (viral).- Cholestasis from systemic disorders Sarcoid, lymphoma, granulomatous disease, cystic fibrosis, rheumatologic diseases.- Complications of cholestasis Osteoporosis Pruritus Lipids.- Cholestasis post transplantation Drugs, strictures, viral disease, recurrent cholestatic liver disease.
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