Neoplastic Diseases of the Blood integrates the history, epidemiology, pathology, pathophysiology, and therapeutics of modern neoplastic hematopathology. The book is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia— Chronic Leukemias and Related Disorders , Acute Leukemias, Myeloma and Related Disorders, and Lymphomas. The fifth section covers a variety of topics in supportive care. Now in its fifth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. Chapters feature an accessible and easy-to-read layout and provide updates on the tremendous progress made in the last decade in the understanding of the nature of hematologic malignancies and their treatment. An authoritative and indispensable resource for students, trainees, and clinicians, this fifth edition is sure to distinguish itself as the definitive reference on this topic.
Spis treści
A History of the Chronic Leukemias.- Etiology and Epidemiology of Chronic Myeloid Leukemia.- Pathology of the Chronic Myeloid Leukemias.- Molecular Biology and Cytogenetics of Chronic Myeloid Leukemia.- Diagnosis and Treatment of Chronic Myeloid Leukemia.- Etiology and Epidemiology of CLL.- Histopathology, Morphology, and Immunophenotyping of CLL.- Molecular Biology and Cytogenetics of Chronic Lymphocytic Leukemia.- Treatment of Chronic Lymphocytic Leukemia and Related Disorders.- Hairy Cell Leukemia.- The Pathogenesis, Diagnosis, and Treatment of Polycythemia Vera.- Diagnosis and Treatment of Essential Thrombocythemia and Primary Myelofibrosis.- History of Acute Leukemia.- The Etiology of Acute Leukemia.- Epidemiology and Hereditary Aspects of Acute Leukemia.- Classification of the Acute Leukemias: Cytochemical and Morphologic Considerations.- Immunobiology of Acute Leukemia.- Cytogenetics of Acute Leukemia.- Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia.- Diagnosis and Treatment of Adult Acute Lymphoblastic Leukemia.- Diagnosis and Treatment of Childhood Acute Myeloid Leukemia.- Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other Than Acute Promyelocytic Leukemia.- Acute Promyelocytic Leukemia.- Therapy-Related Acute Myelogenous Leukemia.- The Myelodysplastic Syndromes.- History of Multiple Myeloma.- Cytokines and Signal Transduction in Multiple Myeloma.- Epidemiology of Multiple Myeloma.- Immunoglobulins and Laboratory Recognition of Monoclonal Proteins.- Cytogenetic Abnormalities in MGUS and Myeloma.- Molecular Genetics of Myeloma.- Prognosis and Staging of Multiple Myeloma.- Diagnosis and Treatment of Multiple Myeloma.- Complications and Special Presentations of Plasma Cell Myeloma.- Waldenström’s Macroglobulinemia.- Heavy-Chain Disease.- Diagnosis and Therapy of Immunoglobulin Light Chain Amyloidosis (AL Amyloidosis).- Monoclonal Gammopathy of Undetermined Significance.- Historical Landmarks in the Understanding of the Lymphomas.- Genetics in Lymphomagenesis.- Epidemiology and Hereditary Aspects of Hodgkin and Non-Hodgkin Lymphomas.- Pathology of Non-Hodgkin and Hodgkin Lymphomas.- Immunology of the Lymphomas.- Cytogenetics of Lymphomas.- Diagnosis and Treatment of Hodgkin’s Lymphoma.- Radiotherapeutic Management of Lymphomas.- Diagnosis and Treatment of Non-Hodgkin’s Lymphoma of Adults.- Non-Hodgkin Lymphoma of Childhood.- Lymphoma in Other Diseases.- Supportive Care for Patients with Leukemia: A Historical Perspective.- Prevention of Infections in Patients with Hematological Malignancies.- Evaluation and Management of Bacterial and Fungal Infections Occurring in Patients with a Hematological Malignancy: A 2011 Update.- Viral Infections in Patients with Hematological Malignancies.- Therapeutic Cytapheresis, Plasmapheresis, and Plasma Exchange in Neoplastic Diseases of the Blood.- Red Cell Transfusions in Patients with Hematologic Malignancies.- Platelet and Granulocyte Transfusion.- Alternative Sources of Hematopoietic Stem Cells and Their Clinical Applications.- HLA Typing in Support of Hematopoietic Cell Transplantation from Unrelated Donors.- Special Care of Blood and Marrow Stem Transplant Patients.- Hematopoietic Growth Factors in the Supportive Care and Treatment of Patients with
Hematologic Neoplasms.- Bleeding and Thrombosis in Hematologic Neoplasia.- Psychological Aspects of Hematological Neoplasms.-
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