A textbook which is both comprehensive and comprehensible and that offers easy but scientifically sound reading to both students and professionals
Now in its 12th edition in its native German, Voigt’s Pharmaceutical Technology is an interdisciplinary textbook covering the fundamental principles of pharmaceutical technology. Available for the first time in English, this edition is produced in full colour throughout, with a concise, clear structure developed after consultation with students, instructors and researchers. This book:
* Features clear chapter layouts and easily digestible content
* Presents novel trends, devices and processes
* Discusses classical and modern manufacturing processes
* Covers all formulation principles including tablets, ointments, capsules, nanosystems and biopharmaceutics
* Takes account of legal requirements for both qualitative and quantitative composition
* Addresses quality assurance considerations
* Uniquely relates contrasting international pharmacopeia from EU, US and Japan to formulation principles
* Includes examples and text boxes for quicker data assimilation
Written for both students studying pharmacy and industry professionals in the field as well as toxicologists, biochemists, medical lab technicians, Voigt’s Pharmaceutical Technology is the essential resource for understanding the various aspects of pharmaceutical technology.
Tabela de Conteúdo
Contributors vii
Foreword ix
Acknowledgements xiii
List of Abbreviations xv
Index of Pharmacopeia Boxes xix
Part I Dosage Forms
1 Drug Formulations as Application System-Science and Legal Provisions 3
Part II General and Technological Principles and Unit Operations
2 Unit Operations 13
3 Physical and Physicochemical Principles of Drug Formulation 39
4 Sterilization of Drug Formulations: Procedures to Reduce Microbial Count 133
5 Excipients for Drug Formulation 161
6 Basic Principles of Probability and Statistics 241
7 Basic Principles in Biopharmaceutics 279
Part III Solid Dosage Forms
8 Powders and Granules 319
9 Tablets 345
10 Coated Oral Dosage Forms 377
11 Capsules 395
12 Peroral Modified Release (MR) Formulations 409
13 Rectal Preparations 429
14 Vaginal Dosage Forms and Dosage Forms to be Introduced in Body Cavities 447
Part IV Semi-solid Dosage Forms
15 Semi-Solid Preparations for Cutaneous Application 453
16 Patches/Plasters 517
Part V Liquid Dosage Forms
17 Solutions 529
18 Emulsions 537
19 Suspensions 557
20 Micro- and Nanodispersed Systems 569
21 Parenteral Formulations 581
22 Ophthalmic Preparations 623
Part VI Gaseous Dosage Forms
23 Inhalation Dosage Forms 637
Part VII General Aspects of Dosage Forms
24 Herbal Drug Preparations (Extracts, Tinctures, and Aqueous Preparations) 659
25 Stability and Stabilization 681
26 Incompatibilities 707
27 Packaging Materials and Technology 721
28 Recent and Future Developments in Pharmaceutical Technology 749
Appendix A Selected Dosage Forms (Compared between Ph. Eur., USP, and JP) 757
Index 817
Sobre o autor
Prof. Dr. Alfred Fahr is Professor Emeritus in Pharmaceutical Technology at the Institute of Pharmacy, Friedrich-Schiller University of Jena, Germany. He was Head of laboratory at Sandoz Pharma (now Novartis) between 1986 and 1996 responsible for Biopharmaceuticals, Human Pharmacology and Drug Delivery Systems, and spent six years at Philipps-Universität Marburg in the Faculty of Pharmacy and Food Chemistry before joining Friedrich-Schiller University of Jena in 2002. His research interests include biophysics of modern formulations, mechanisms of skin penetration and non-viral gene therapy, nanotechnological formulations in pharmacy and formulations of poorly soluble active substances.
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