This monograph is a self-contained, coherent presentation of the background and progress of the stability of time-delay systems. Focusing on techniques, tools, and advances in numerical methods and optimization algorithms, the authors developed material which, up until now, has been scattered in technical journals and conference proceedings. Special emphasis is placed on systems with uncertainty and stability criteria which can be computationally implemented. The second edition is major update to reflect the state of art in this field greatly expanding on the original material in addition to two new chapters on Systems of Neutral Type and an Introduction to Frequency Domain Method. Requiring only basic knowledge of linear systems and Lyapunov stability theory, Stability of Time-Delay Systems, 2nd ed is accessible to a broad audience of researchers, professional engineers, and graduate students. It may be used for self-study or as a reference; portions of the text may be used in advanced graduate courses and seminars.