This unique handbook provides a comprehensive survey of the present status of Technetium chemistry and its radiopharmaceutical applications. All Technetium aspects such as
· natural and artificial occurence in the environment,
· isotopes and isomers,
· analytical chemistry and electrochemistry,
· thermodynamic data, stability and reactivity,
· intermetallic and binary compounds, and predominantly
· complex chemistry, and
· radiopharmacy
are presented in an clear and precise manner. This outstanding presentation allows both experts and non-experts a quick access to the subject. Therefore this handbook is an indispensable reference for researchers at universities and research centers, in the nuclear medicine and radiopharmaceutical industries as well as consultants in government and environmental agencies.
Tabela de Conteúdo
A CHEMISTRY
Introduction
Discovery
Natural occurrence
Artificial occurrence
Isotopes and isomers
Some fundamentals of technetium chemistry
Analytical chemistry
Uses of technetium-99
Technetium metal
Binary compounds and oxide halides
Oxotechnetates
Complex chemistry of technetium-99
B 99M-TC RADIOPHARMACEUTICAL APPLICATIONS
Introduction
Generation of 99m Tc
Imaging of organs
Synthesis aspects and requirements
Kits
Synthesis, structure, and development
Brain perfusion imaging agents
Myocardial perfusion imaging agents
Thyroid imaging…
Lung imaging…
Hepatobiliary imaging agents
Renal imaging agents
Bone imaging agents
Tumor imaging agents
Some future prospects
Summary of 99m Tc radiopharmaceuticals
C APPENDIX
Acronyms and abbreviations used in parts A and B