Adolescents frequently present to the emergency department or to primary care physicians for acute health concerns that range from minor to life-threatening. This issue of AM:STARs focuses on many of the more urgent and emergent health problems and concerns that bring adolescents to clinics, private offices, and emergency department settings. Topics include:Female adolescent gynecology emergencies Male adolescent genitourinary emergencies Sports-related head injuries and concussions Approach to the adolescent with chest pain Mental health/psychiatric emergencies Substance use and abuse/overdose Approach to the adolescent with syncope Emergency care of youth with social and environmental vulnerabilities