The Receptors, Volume IV deals with receptors for intracellular hormones, estrogen, and sex steroids as well as for dopamine, cholecystokinin, and corticotropin. The role of surface recognition receptors in disease is also discussed, along with receptors for plant auxin action and auxin transport. Comprised of 11 chapters, this volume begins with a detailed account of the ?-adrenergic receptor-coupled adenylate cyclase and the reconstitution of the functional interactions of its various purified components. The discussion then turns to the mechanism of action of steroid and thyroid hormones and how abnormalities in their receptors lead to disease; nuclear location of estrogen receptors; and the biochemistry of the fungal sex steroid receptors as well as the use of Achlya as a model system for the study of the mechanism of action of steroid hormones in general. Subsequent chapters focus on dopamine receptors; cholecystokinin receptor; corticotropin receptors; and the search for receptors that mediate sweetness. The book concludes with an analysis of endocrine receptors on lymphocytes and the integration of endocrine and immune systems, with emphasis on large granular lymphocytes. This monograph will be a valuable resource for students and practitioners in fields ranging from cell biology and biochemistry to physiology, endocrinology, and pharmacology.
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