T. Smollett 
The Expedition of Humphry Clinker [EPUB ebook] 

The pills are good for nothing—I might as well swallow snowballs to cool my reins—I have told you over and over how hard I am to move; and at this time of day, I ought to know something of my own constitution. Why will you be so positive? Prithee send me another prescription—I am as lame and as much tortured in all my limbs as if I was broke upon the wheel: indeed, I am equally distressed in mind and body—As if I had not plagues enough of my own, those children of my sister are left me for a perpetual source of vexation—what business have people to get children to plague their neighbours? A ridiculous incident that happened yesterday to my niece Liddy, has disordered me in such a manner, that I expect to be laid up with another fit of the gout—perhaps, I may explain myself in my next.