When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity.
Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.
Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.
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About the author
Rebecca Mertens is a postdoctoral researcher in the collaborative research center 1288 »Practices of Comparing«. Her research interests cover the role of analogies, models and forms of comparison in the history of the life sciences.Buy this ebook and get 1 more FREE!
Language English ● Format PDF ● Pages 224 ● ISBN 9783839444429 ● File size 2.8 MB ● Publisher transcript Verlag ● City Bielefeld ● Country DE ● Published 2019 ● Edition 1 ● Downloadable 24 months ● Currency EUR ● ID 6406163 ● Copy protection Social DRM
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