Advances in Controlled Clinical Inhalation Studiesrepresents scientific work presented at the 3rd International Inhalation Symposium held 1991 in Hannover, FRG. The symposium covered the new developments in thisfield of research. The main pollutants of interest were acidaerosols, fog, and indoor pollutants, while with regard tobiological effects, an emphasis was placed onimmunotoxicological and biochemical parameters. Tests onhigh risk groups were also considered. Initial chaptersdescribe the outdoor environment as well as indoor air, measurement and quality – both at home and in the workplace. Besides methods for clinical inhalation and assessingpersonal exposure, new methodologies are particularlypresented. Further chapters focus on the relevance ofclinical data for regulatory decisions.