Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective – and prevent the destructive – mechanisms of gliosis.
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Cuprins
Introduction.- Basic properties of Müller cells.- Müller cell gliosis.- Müller cells in the healthy retina.- Retinal Development.- Müller cells as ‘light cables’.- Soft Müller cells as shock absorbers and axon paths.- ‘Metabolic symbiosis’.- Neurotransmitter recycling.- Retinal K+ homeostasis.- Retinal water homeostasis.- Other interactions.- Müller cells in the diseased retina.- Retinal detachment.- Diabetic retinopathy.- Macular edema.- Proliferative retinopathies.- Ischemia-reperfusion.- Hepatic retinopathy.- Retinoschisis.- Retinitis pigmentosa and support of neuronal survival.- Future directions.- Index.Cumpărați această carte electronică și primiți încă 1 GRATUIT!
Limba Engleză ● Format PDF ● Pagini 417 ● ISBN 9781441916723 ● Mărime fișier 10.9 MB ● Vârstă 02-99 ani ● Editura Springer New York ● Oraș NY ● Țară US ● Publicat 2010 ● Descărcabil 24 luni ● Valută EUR ● ID 2150027 ● Protecție împotriva copiilor DRM social
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