In this issue of Hematology/Oncology Clinics, guest editor Dr. David E. Fisher brings his considerable expertise to the topic of Cutaneous Oncology. Top experts first provide information on skin structure, function, and immunology, then offer overviews of the therapeutic state of the art for both melanoma and non-melanoma skin cancers. Discussions focus on unique clinical challenges and biological breakthroughs which have come to light in recent studies of cutaneous malignancies. – Contains 16 relevant, practice-oriented topics including high risk non-melanoma skin cancers; progress in immune checkpoints for melanoma therapy; targeted therapy innovations for melanoma; advances in vaccines for melanoma; microbiome and immunotherapy; Merkel cell carcinoma; and more. – Provides in-depth clinical reviews on cutaneous oncology, offering actionable insights for clinical practice. – Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.