This volume represents the proceedings of the conference on Topics in Deformation Quantization and Non-Commutative Structures held in Mexico City in September 2005. It contains survey papers and original contributions by various experts in the fields of deformation quantization and non-commutative derived algebraic geometry in the interface between mathematics and physics. It also contains an article based on the XI Memorial Lectures given by M. Kontsevich, which were delivered as part of the conference. This is an excellent introductory volume for readers interested in learning about quantization as deformation, Hopf algebras, and Hodge structures in the framework of non-commutative algebraic geometry.