Cocaine poses interesting problems for neurophysiologists and neuropharmacologists and there is important new data on the effects of cocaine on the brain (its initial site of action at the cellular level now appearing to be the dopamine transporter). Includes chapters on the far-reaching toxic effects of cocaine, on the epidemiology and the economics of drug addiction, on the past and present use of cocaine in the U.S. and in South America, and on the moral issues raised by drug use and abuse.
Cuprins
Partial table of contents:
Cocaine in Perspective (G. Edwards).
Cocaine’s History, Especially the American Experience (D.
Musto).
Epidemiological Research on Cocaine Use in the USA (J.
Anthony).
Cocaine Problems in the Coca-Growing Countries of South America
(J. Negrete).
Are There „Casual Users” of Cocaine?
(C. Kaplan, et al.).
Molecular Pharmacology of Cocaine: A Dopamine Hypothesis and Its
Implications (M. Kuhar).
The Neurobiology of Cocaine-Induced Reinforcement (H. Fibiger,
et al.).
How Toxic Is Cocaine?
(N. Benowitz).
Determinants of Cocaine Self-Administration by Laboratory
Animals (W. Woolverton).
Treatment of Cocaine Abuse: Pharmacotherapy (H. Kleber).
Alternative Strategies (R. Jones).
The Economics of Drug Use and Abuse (A. Maynard).
Drug Use and Abuse: The Ethical Issues (B. Almond).
Indexes.
Despre autor
The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
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