This book constitutes the refereed proceedings of the 16th International Conference on Data Warehousing and Knowledge Discovery, Da Wa K 2014 held in Munich, Germany, September 2014, in conjunction with DEXA 2014. The 34 revised full papers and 8 short papers presented were carefully reviewed and selected from 109 submissions. The papers are organized in topical sections on modeling and ETL; ontology-based data warehouses; advanced data warehouses and OLAP; uncertainty; preferences and recommendation; query performance and HPC; cube & OLAP; optimization; classification; social networks and recommendation systems; knowledge data discovery; industrial applications; mining and processing data stream; mining and similarity.