This book, which is the second volume of Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases, provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting in autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases.
Contributions in the book focus on the role of microbiota/probiotics and their distinct mechanisms exerted in the management of autoimmune diseases of the kidney, central nervous system, eye, blood vessel, and bowel. This could help in better understanding to design of therapeutic strategies that can be deployed to prevent these autoimmune diseases.
The book has an interdisciplinary appeal and scholars with an interest in immunology, medical microbiology, and nutritional sciences will value its contribution. Overall, the book gives new dimension and insight into the aspects of microbial role in autoimmune disease pathogenesis.
Cuprins
PART I: HUMAN MICROBIOME, VACCINES AND AUTOIMMUNITY.- Chapter 1. Autoimmunity and Microbiome.- Chapter 2. The vaccines induced autoimmunity.- Chapter 3. COVID-19 and Autoimmunity.- Chapter 4. The protective discourse between infections and autoimmunity.- PART II: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE KIDNEY DISEASES & ADRENAL INSUFFICIENCY.- Chapter 5. Microorganisms in pathogenesis and management of Anti-Neutrophil Cytoplasmic Antibody- (ANCA)- Associated Vasculitis.- Chapter 6. Microorganisms in pathogenesis and management of Ig A Vasculitis and Ig A Nephropathy.- Chapter 7. Microorganisms in pathogenesis and management of immune mediated glomerulopathies.- Chapter 8. Microorganisms in pathogenesis and management of Autoimmune Addison’s Disease (ADD).- PART III: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF CENTRAL NERVOUS SYSTEM (CNS) DEMYELINATING AUTOIMMUNE DISEASES.- Chapter 9. Microorganisms in pathogenesis and management of Multiple Sclerosis (MS).- Chapter 10. Microorganisms in pathogenesis and management of Guillain-Barre syndrome (GBS).- Chapter 11. Microorganisms in pathogenesis and management of Neuromyelitis Optica.- Chapter 12. Microorganisms in pathogenesis and management of Acute Disseminated Encephalomyelitis (ADEM).- PART IV: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF INFLAMMATORY BOWEL DISEASES (IBDs).- Chapter 13. Microorganisms in pathogenesis and management of Ulcerative colitis (UC).- Chapter 14. Microorganisms in pathogenesis and management of Crohn’s disease (CD).- Chapter 15. Microorganisms in pathogenesis and management of Pouchitis.- Chapter 16. Microorganisms in pathogenesis and management of Coeliac Disease.- PART V: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE BLOOD & BLOOD VESSEL DISORDERS.- Chapter 17. Microorganisms in pathogenesis and management of Anti-Phospholipid Syndrome (Hughes syndrome).- Chapter 18. Microorganisms in pathogenesis and management of Behçet Disease (BD).- Chapter 19. Microorganisms in pathogenesis and management of Immune Thrombocytopenia.- PART VI: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE EYE DISEASES.- Chapter 20. Microorganisms in pathogenesis and management of Autoimmune Uveitis.- Chapter 21. Microorganisms in pathogenesis and management of Autoimmune Retinopathy (AIR).- Chapter 22. Microorganisms in pathogenesis and management of Type 1 Diabetes (T1D).- Chapter 23. The influence of the microbiome and genetic associations on immune functions and on autoimmune and autoinflammatory diseases.- Chapter 24. Current challenges in research with exploring the microbial pathomechanisms of Autoimmune diseases.- Chapter 25. Future therapeutic prospects in dealing with autoimmune diseases: Treatment Based on the Microbiome Model.
Despre autor
Dr. Mitesh Kumar Dwivedi is an Assistant Professor of Microbiology at C. G. Bhakta Institute of Biotechnology, Uka Tarsadia University. He has published 55 research papers in reputed journals, written 34 book chapters, and is the editor of 6 books. He has an h-index of 22 with 1711 citations for his research papers. He has more than 15 years of experience in research and teaching in various allied fields of microbiology and immunology. He has contributed significantly in the field of vitiligo- a skin autoimmune depigmenting disorder. His current research interests include investigation of immunogenetic, autoimmune & therapeutic aspects of Vitiligo, Rheumatoid arthritis, Sickle cell disease and role of Probiotics in ameliorating the autoimmune diseases. He has been serving as an editorial board member and reviewer of many international journals. He has been honored with many international and national awards for his excellent research performance [DST-SERB Core Research Grant (2022), SERB-SIRE International Research Fellowship (2022), Best Researcher Award (2020), INSA Visiting Scientist Award (2019), DST-SERB Early Career Research Award (2018), Young Scientist Awards (2011, 2013, and 2018)] and secured all India rank ‘32’ in CSIR-NET National examination (2011; Life Sciences). He has successfully completed 05 research projects as Principal Investigator from national funding agencies such as SERB-DST, GUJCOST, UTU, and Neosciences & Research Solutions Pvt. Ltd. and guided students for their doctoral and master degrees.
Dr. A. Sankaranarayanan is an Associate Professor in Department of Life Sciences, Sri Sathya Sai University for Human Excellence, Kalaburagi, Karnataka, India from June 2021 onwards. His current research focus is on fermented food products. He has published 10 books, 35 chapters, 63 research articles in International and National journals of repute, guided 5 Ph.Ds, 16 M.Phil, scholars and operated 5 minor funded projects in Microbiology. From 2002 -2015, he worked as an Assistant Professor & Head, Department of Microbiology, K.S.R. College of Arts & Science, Tiruchengode, Tamil Nadu and August, 2015- May, 2021 associated with Uka Tarsadia University, Surat, Gujarat, India. He has awarded with Indian Academy of Sciences (IASc), National Academy of Sciences (NAS) and The National Academy of Sciences (TNAS) sponsored summer research fellowship for young teachers consecutively for three years and name is included as a Mentor in DST-Mentors/Resource persons for summer/winter camps and other INSPIRE initiatives, Department of Science & Technology, Govt. of India, New Delhi. He is a Grant reviewer in British Society of Antimicrobial Chemotherapy (BSAC), UK.
Dr. E. Helen Kemp completed her Ph D in Microbiology at the University of Warwick and the Centre for Applied Microbiology and Research, Salisbury, in 1988. Since 1989, she has worked at the University of Sheffield as a Research Fellow in the Medical School. She has long-standing interests in the autoimmune and genetic aspects of the depigmenting disease vitiligo, characterising autoimmune responses against the calcium-sensing receptor in patients with parathyroid autoimmunity, and the aetiology of autoimmune thyroid disease. She has published more than 70 research papers in these areas of research and has contributed to books and review articles in the field of autoimmunity.
Professor Yehuda Shoenfeld is the founder and head of the Zabludowicz Center for Autoimmune Diseases, at the Sheba Medical Center, which is affiliated to the Sackler Faculty of Medicine in Tel-Aviv University, in Israel. Professor Shoenfeld is also the Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at the Tel-Aviv University. Professor Shoenfeld’s clinical and scientific works focus on autoimmune and rheumatic diseases, and he has published more than 2250 papers in journals such as New Eng J Med, Nature, Lancet, Proc Nat Acad Scie, J Clin Invest, J Immunol, Blood, FASEB, J Exp Med, Circulation, Cancer and others. His articles have had over 65, 000 citations. His Scopus h-index is 123. He has written more than 350 chapters in books, and has authored and edited 35 books, some of which became cornerstones in science and clinical practice, such as ‘The Mosaic of Autoimmunity’, ‘Infections and Autoimmunity’ and the textbook ‘Autoantibodies’ and ‘Diagnostic criteria of autoimmune diseases’, all of which were published by Elsevier and sold thousands of copies. Professor Shoenfeld is on the editorial boards of 43 journals in the field of rheumatology and autoimmunity and is the founder and the editor of the IMAJ (Israel Medical Association Journal) the representative journal of science and medicine in the English language in Israel, and also is the founder and Editor of Autoimmunity Reviews (Elsevier) (Impact factor 9.975) and co-Editor of the Journal of Autoimmunity (Impact factor 7.o). For the past twenty years Yehuda has been the Editor of “Harefuah” – The Israel journal in medicine (Hebrew). Professor Shoenfeld received the EULAR prize in 2005, in Vienna, Austria: ‘The infectious etiologyof anti-phospholipid syndrome’, and received a gold medal from the Slovak Society of Physicians for his contribution to Israel – Slovakia collaboration (March 2006). He is also an honorary member of the Hungarian Association of Rheumatology and the Royal Society of Physicians (UK). In UC Davis, USA, Professor Shoenfeld received the Nelson’s Prize for Humanity and Science for 2008. In 2009 he was honoured as Doctoris Honoris Causa, from Debrecen University (Hungary) and Hasselt University in Belgium( 2018) , and from 2009 he is honorary member of the Slovenian National Academy of Sciences. He was recently awarded a Life Contribution Prize in Internal Med^55 becoming heads of departments and institutes.
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