Neocles Leontis & Eric Westhof 
RNA 3D Structure Analysis and Prediction [PDF ebook] 

Ajutor

With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone.  This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.

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Cuprins

RNA Polymerases and Transcription Factors of Trypanosomes.- SL RNA biogenesis in kinetoplastids: a long and winding road.- Pre-m RNA splicing in Trypanosoma brucei: factors, mechanisms, and regulation.- m RNA turnover in trypanosomes.- t RNA biogenesis and processing.- r RNA biogenesis in trypanosomes.- RNA Editing in African Trypanosomes – a User’s Guide.- The RNA Interference Pathway in Trypanosoma brucei.- Translation in trypanosomatids.- Mitochondrial translation in trypanosomatids.- RNA-Seq analysis of the transcriptome of Trypanosoma brucei.

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Limba Engleză ● Format PDF ● Pagini 402 ● ISBN 9783642257407 ● Mărime fișier 10.9 MB ● Editor Neocles Leontis & Eric Westhof ● Editura Springer Berlin ● Oraș Heidelberg ● Țară DE ● Publicat 2012 ● Descărcabil 24 luni ● Valută EUR ● ID 2477309 ● Protecție împotriva copiilor DRM social

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