Aimed at synthetic organic chemists in academia and industry, the book summarizes recent developments in the preparation of nitroalkanes, their functionalization, and application for the synthesis of important heterocycles, natural products, and bioactive compounds.
Table of Content
Introduction
Synthesis of Nitroalkanes
Reduction of the Nitro Group into Amines
The Nef Reaction
Nitroaldol (Henry) Reaction
Conjugate Addition of Nitroalkanes to Electron-Poor Alkenes (Michael Reaction)
Formation of C, C Bond by Coupling Nitroalkanes with Arylhalides
Synthesis and Reactivity of 1, 3-Dinitroalkanes
Formation of Carbon-Carbon Double Bonds via Nitrous Acid Elimination (NAE)
alpha-Nitrocycloalkanones, Synthesis and Reactivity
Acyclic alpha-Nitro Ketones: Synthesis and Reactivity
Nitro Cyclopropanes: Synthesis and Applications
Nitroalkanes as Source of Dicarbonyls
Nitroalkanes as Source of Spiroketals
About the author
Roberto Ballini is Professor of Organic Chemistry at the University of Camerino, Italy. His research is mainly dedicated to organic synthesis, with particular emphasis on aliphatic nitro compounds. He has published more than 250 articles and edited two books.
Alessandro Palmieri is Associate Professor at the University of Camerino, Italy. He develops eco-friendly processes for the formation of C-C and C-X bonds, and flow chemical protocols for the synthesis of fine chemicals. He is co-author of 100 publications.
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