Tailoring of biomolecules using protein engineering technology, and host cells culture techniques are among the most sophisticated and elegant achievements of modern applied life sciences in which the basic fundamentals biotechnology are applicable for the development and manufacturing of biologics and other related bio-molecules for a hurdle free life with good health. A majority of biologics derived from genetically modified host cells in the current market are bio-formulation such as antibodies, nucleic acid products and vaccines. Such bio-formulations are developed mainly in two steps i.e. upstream process and downstream process. The first volume of this series begins with the latest information on how the classical stepwise host cells culture (mammals, animals, plants, and bacteria) methodology has been changed to fully continuous or partially continuous host cells culture process in order to economise the biopharmaceutical products manufacturing process. In addition this volume narrates a brief history on conceptual development of new thoughts in designing biotechnology industries for commercial production of variety of therapeutic proteins with structural modification on the basis of clinical requirements. The readers will feel exited by going through the latest discovery and development in applied life sciences for designing innovative biomolecules for health care with utmost safe. The most interesting part of this volume is newly developed concept on bioprinting. It explains how to design and fabricate animate objects by fusing or depositing material of interest in the form of powders, solid dusts, metal, liquid or even living cells or tissues by layers to produce 3D objectives. The first volume ends with the latest information on the current trend in biologics market, market dynamic, drives, and opportunities with challenges.
Содержание
Chapter 1. Strategies in Life sciences.- Chapter 2. Management and Manufacturing process of biologics.- Chapter 3. Downstream processes.- Chapter 4. Bioprinting .- Chapter 5. Biopharmaceuticals: New Frontier.
Об авторе
Dr. Basanta Kumara Behera was a professor of biotechnology at three distinguished Indian universities, where he had been regularly associated with teaching and research at post graduate level courses on the topic related to biomass process technology development, biopharmaceuticals, microbial process development, drug designing, bio-energy management and biomass processing technology since 1978. In 2009 he joined a MNS company as adviser for speciality chemicals production and drug design through microbial process technology. Prof. Behera is associated with national and international repute companies as technical adviser for the production of biopharmaceuticals under c GMP norms. Dr Behera has credit of being authored books published/in process by CRC Press USA, Springer Verlag, Germany, Elsevier Inc. Cambridge, CABI, Nosworthy Way Wallingford Oxfordshire.
Dr.Ram Prasad, is associated with Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, India. His research interest includes applied & environmental microbiology, plant-microbe-interactions, sustainable agriculture and nanobiotechnology. Dr. Prasad has more than one hundred fifty publications to his credit, including research papers, review articles & book chapters and five patents issued or pending, and edited or authored several books. Dr. Prasad has twelve years of teaching experience and has been awarded the Young Scientist Award & Prof. J.S. Datta Munshi Gold Medal by the International Society for Ecological Communications; FSAB fellowship by the Society for Applied Biotechnology; the American Cancer Society UICC International Fellowship for Beginning Investigators, USA; Outstanding Scientist Award in the field of Microbiology by Venus International Foundation; BRICPL Science Investigator Award and Research Excellence Award etc. He has been serving as editorial board members: Frontiers in Microbiology, Frontiers in Nutrition, Archives of Phytopathology and Plant Protection, Phyton- International Journal of Experimental Botany; Academia Journal of Biotechnology, Journal of Renewable Materials including Series editor of Nanotechnology in the Life Sciences, Springer Nature, USA. Previously, Dr. Prasad served as Assistant Professor Amity University Uttar Pradesh, India; Visiting Assistant Professor, Whiting School of Engineering, Department of Mechanical Engineering at Johns Hopkins University, Baltimore, United States and Research Associate Professor at School of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou, China.
Dr. Shyambhavee Behera is a medical graduate from Lady Hardinge Medical College, New Delhi, and MD degree holder from University College of Medical Science, New Delhi. She has been working in the field of Non-communicable disease, immunization, maternal and child health, epidemiology and health administration to upgrade and bring amendments in community for sustainable life pattern with good health. She is presently associated with Department of Community Medicine, Atal Bihari Vajpayee Institute of Medical Sciences & Dr. RML as senior resident. Hospital, New Delhi, Govt. of India. She is co-author for a book entitled “Move Toward Zero Hunger” Springer Nature, Singapore Pte. Ltd.
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