Board on Health Sciences Policy & Committee on Accelerating Rare Diseases Research and Orphan Product Development 
Rare Diseases and Orphan Products [PDF ebook] 
Accelerating Research and Development

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.