Eric P. Hoffman & Claude Bouchard 
The Encyclopaedia of Sports Medicine, An IOC Medical Commission Publication, Volume XVIII, Genetic and Molecular Aspects of Sports Performance [EPUB ebook] 

This is the latest volume in the IOC Encyclopaedia of Sports
Medicine series, summarizing the evidence from all relevant
sources on the genetic and molecular basis of sports and other
human physical performance.

The initial chapters address the basic science of genomics and
genetics and the regulation of gene expression. Additional
chapters provide authoritative information on the genetics of
complex performance phenotypes, the contributions of small animal
research, family and twin studies, and ethnic comparisons. A
final section addresses the issue of the contribution of specific
genes and molecular markers as related to endurance, strength and
power, and responsiveness to specific conditioning
programs.

This latest volume in the Encyclopaedia of Sports Medicine
Series from the Medical Commission of the International Olympic
Committee is a must for sports and exercise scientists who require
a thorough guide to the most cutting edge science in this expanding
field.

Содержание

List of Contributors.

Foreword.

Preface.

Part 1 The Science of Genomics and Genetics.

1 The Human Genome and Epigenome (john j. mulvihill, klaas j.wierenga and chad m. kerksick).

2 Mitochondrial Medicine in Health and Disease: Interface Between Athletic Performance and Therapeutics (douglas c.wallace).

3 Characterizing the Extent of Human Genetic Variation for Performance-Related Traits (john blangero and jack w. kentjr.).

4 Current Proteome Profiling Methods (yetrib hathout, catherinea. formolo, kristy j. brown and javad nazarian).

5 Bioinformatics and Public Access Resources (yue wang, huai li, david j. miller and jianhua xuan).

6 Search for Genes Influencing Complex Traits (corneliu henegar, henri hooton and karine clément).

Part 2 Evidence from Genetic Epidemiology Studies.

7 Genetic Epidemiology, Physical Activity, and Inactivity (mollys. bray, janet e. fulton, nishan sudheera kalupahana and j. timothylightfoot).

8 Role of Genetics Factors in Sport Performance: Evidence from Family Studies (louis pérusse).

9 Twin Studies in Sport Performance (gaston p. beunen, maartenw. peeters and robert m. malina).

10 Twin and Family Studies of Training Responses (mark a.sarzynski, tuomo rankinen and claude bouchard).

11 Ethnic Differences in Sport Performance (yannis p.pitsiladis).

12 Selection Experiments in Rodents to Define the Complexity and Diversity of Endurance Capacity (steven l. britton and laurengerard koch).

Part 3 Contributions of Specific Genes and Markers.

13 Genes and Endurance Performance (bernd wolfarth).

14 Genes and Strength and Power Phenotypes (martine a.i.thomis).

15 Genes and Response to Training (tuomo rankinen, mark a.sarzynski and claude bouchard).

16 Genetic Determinants of Exercise Performance: Evidence from Transgenic and Null Mouse Models (eunhee chung and leslie a.leinwand).

17 The ACE Gene and Performance (james r.a. skipworth, zudin a. puthucheary, jai rawal and hugh e. montgomery).

18 The ACTN3 Gene and Human Performance (daniel g.macarthur and kathryn n. north).

19 Mitochondrial DNA Sequence Variation and Performance (shinyakuno, hirofumi zempo and haruka murakami).

20 Genes, Exercise, and Lipid Metabolism (yohan bossé).

21 Genes, Exercise, and Glucose and Insulin Metabolism (leonidasg. karagounis and john a. hawley).

22 Genes, Exercise, and Cardiovascular Phenotypes (james m.hagberg).

23 Genes, Exercise, and Protein Metabolism (mark a.tarnopolsky).

24 The Regulation of Physical Activity by Genetic Mechanisms: Is There a Drive to Be Active? (nishan sudheera kalupahana, naimamoustaid-moussa, jung han kim, brynn h. voy, david bassett, mollys. bray and j. timothy lightfoot).

25 Genes, Exercise, and Psychological Factors (eco j.c. de geusand marleen h.m. de moor).

Part 4 Systems Biology of Exercise and Training.

26 A Primer on Systems Biology, as Applied to Exercise Physiology and Metabolism (james a. timmons and jorn w. helge).

27 Systems Biology Through Time Series Data—A Strength of Muscle Remodeling (monica hubal, zuyi wang and

eric p. hoffman).

28 Proteomics in Exercise Training Research (dustin s.hittel).

29 The Influence of Physical Exercise on Adult Stem Cells (fawzikadi).

Part 5 Ethical and Societal Implications.

30 Genetics and Ethics in Elite Sport (sigmund loland).

31 Genes and Talent Selection (stephen m. roth).

32 Performance Enhancement by Gene Doping (anna baoutina).

33 Bioethical Concerns in a Culture of Human Enhancement (andymiah).

Index.

Об авторе

Professor Claude BOUCHARD, Ph D, Executive Director, Pennington Biomedical Research Center, Baton Rouge, Louisiana, U.S.A.

Professor Eric P. HOFFMAN, Ph D, Director, Research Center for Genetic Medicine, Children’s National Medical Center, Washington DC, U.S.A.