Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex.
This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances — particularly immunopathology and pharmacogenetics — as well as highlighting new adverse drug signals and novel therapies.
Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.
Содержание
Section I: General Considerations .- Chapter 1: Pharmacogenetics of Cutaneous Adverse Drug Reactions.- Chapter 2: Mechanisms of Drug Hypersensitivity.- Chapter 3: Histopathology of Cutaneous Adverse Drug Reactions.- Chapter 4: Skin Tests in Evaluating Drug Eruptions.- Chapter 5: In vitro Drug Allergy Testing.-
Section II: Reaction Patterns .- Chapter 6: Drug-induced urticaria.- Chapter 7: Exanthematous Drug Eruptions.- Chapter 8: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.- Chapter 9: Acute Generalized Exanthematous Pustulosis.- Chapter 10: Drug Reaction Eosinophilia and Systemic Symptoms (DRESS).- Chapter 11: Fixed Drug Eruptions and Generalized Bullous Fixed Drug Eruptions.- Chapter 12: Lichenoid Drug Eruptions.- Chapter 13: Drug-induced Connective Tissue Disorders.- Chapter 14: Drug-induced Vasculitis.- Chapter 15: Drug-induced Autoimmune Bullous Diseases.- Chapter 16: Other Drug-induced Inflammatory Skin Reactions.- Chapter 14: Drug-induced Vasculitis.- Chapter 15: Drug-induced Autoimmune Bullous Diseases.- Chapter 16: Other Drug-induced Inflammatory Skin Reactions.- Chapter 17: Drug-induced Photosensitivity.- Chapter 18: Drug-induced Pruritus Without Primary Rash.- Chapter 19: Drug-induced Nail Changes.- Chapter 20: Drug-induced Hair Changes.- Chapter 21: Drug-induced Pigmentary Disorders.-
Section III: Special Drug Categories .- Chapter 22: Immediate and Delayed Reactions to Beta-lactams.- Chapter 23: Hypersensitivity Reactions to Iodinated Radiocontrast Media.- Chapter 24: Cutaneous Adverse Reactions to Biologic Agents.- Chapter 25: Cutaneous Reactions to Oncologic Targeted Therapy.- Chapter 26 :Cutaneous Reactions to Oncologic Immunotherapy.
Об авторе
Haur Yueh Lee, MBBS, MRCP (UK), FAMS(Dermatology)
Singapore General Hospital
Department of Dermatology
Singapore, 169856, Singapore
Daniel Creamer, MD FRCP
King’s College Hospital
Department of Dermatology
Denmark Hill
London SE5 9RS, UK
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