Structural Bioinformatics was the first major effort to show
the application of the principles and basic knowledge of the larger
field of bioinformatics to questions focusing on macromolecular
structure, such as the prediction of protein structure and how
proteins carry out cellular functions, and how the application of
bioinformatics to these life science issues can improve healthcare
by accelerating drug discovery and development. Designed primarily
as a reference, the first edition nevertheless saw widespread use
as a textbook in graduate and undergraduate university courses
dealing with the theories and associated algorithms, resources, and
tools used in the analysis, prediction, and theoretical
underpinnings of DNA, RNA, and proteins.
This new edition contains not only thorough updates of the
advances in structural bioinformatics since publication of the
first edition, but also features eleven new chapters dealing with
frontier areas of high scientific impact, including: sampling and
search techniques; use of mass spectrometry; genome functional
annotation; and much more.
Offering detailed coverage for practitioners while remaining
accessible to the novice, Structural Bioinformatics, Second
Edition is a valuable resource and an excellent textbook for a
range of readers in the bioinformatics and advanced biology
fields.
Praise for the previous edition:
‘This book is a gold mine of fundamental and practical
information in an area not previously well represented in book
form.’
—Biochemistry and Molecular Education
‘… destined to become a classic reference work for workers at
all levels in structural bioinformatics…recommended with great
enthusiasm for educators, researchers, and graduate
students.’
—BAMBED
‘…a useful and timely summary of a rapidly expanding
field.’
—Nature Structural Biology
‘…a terrific job in this timely creation of a compilation of
articles that appropriately addresses this issue.’
—Briefings in Bioinformatics
Об авторе
Jenny Gu, Ph D, is Assistant Professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, San Diego. This is her first book.
Philip E. Bourne, Ph D, is professor in the Department of Pharmacology at the University of California, San Diego, and Director of Integrated Biosciences at the San Diego Supercomputer Center. He is past president of the International Society for Computational Biology (ISCB). He is author of over 125 peer-reviewed scientific papers and four previous books.
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