At the core of this book are several application areas where Industry 4.0 has been, or can be, applied. This book introduces the Fourth Industrial Revolution, with discussions and reflections that will lead the reader into a deeper understanding of the nature of the concept. This book also reveals various facets that can be applied and utilized for implementation of the concept in various sectors. This book:* Comprehensively discusses skills for Industry 4.0 * Provides insights into the application of Industry 4.0 in the healthcare sector * Presents involvement of Industry 4.0 in current concepts such as supply chain and blockchain * Showcases innovative additive manufacturing to enhance human machine co-working * Includes virtualization and simulation techniques for decision-making in manufacturing and assembly processes This book is primarily written for graduate students and academic researchers in the fields of industrial engineering, manufacturing engineering, mechanical engineering, production engineering, and aerospace engineering.