Edited by JOHN N. PLEVRIS, Professor and Consultant in Gastroenterology and Hepatology, Centre for Liver and Digestive Disorders, The Royal Infirmary, University of Edinburgh, UK PETER C. HAYES, Professor of Hepatology, Liver Unit, The Royal Infirmary, University of Edinburgh, UK PATRICK S. KAMATH, Professor of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA LOUIS M. WONG KEE SONG, Professor of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA