The brain is the body’s most vulnerable organ due to the defined roles of neurons within circuits. Neurons are vastly outnumbered by microglia, astrocytes, oligodendrocytes, macrophages, cells of the blood brain barrier and invading immune cells. These cells display different grades of reactivities and interactions. They integrate their responses and not only change phenotypes but can also completely reprogram after damage to protect the neuronal complexity. The interactions of th...
Содержание
1. Introduction.- 2. The Brain as an Organ.- 3. Life Cycle.- 4. Reactive Microglia and Astrocyte Phenotype Transitions. 5. Transition of Microgli...
Об авторе
Wolfgang Walz is Professor Emeritus of Psychiatry at the University of Saskatchewan, Canada. His Ph D thesis at the Universität Konstanz described for the first time a neu...