The seventh edition of the most authoritative and comprehensive book published on lung function, now completely revised and restructured
Lung function assessment is the central pillar of respiratory diagnosis. Most hospitals have lung function laboratories where patients are tested with a variety of physiological methods. The tests and techniques used are specialized and utilize the expertise of respiratory physicians, physiologists, and technicians. This new edition of the classic text on lung function is a theoretical textbook and practical manual in one that gives a comprehensive account of lung function and its assessment in healthy persons and those with all types of respiratory disorder, against a background of respiratory, exercise, and environmental physiology. It incorporates the technical and methodological recommendations for lung function testing of the American Thoracic Society and European Respiratory Society.
Cotes’ Lung Function, 7th Edition is filled with chapters covering respiratory surveys, respiratory muscles, neonatal assessment, exercise, sleep, high altitude, hyperbaria, the effects of cold and heat, respirable dusts, fumes and vapors, anesthesia, surgery, and respiratory rehabilitation. It also offers a compendium of lung function in selected individual diseases and is filled with more diagrams and illustrative cases than previous editions.
* The only text to cover lung function assessment from first principles including methodology, reference values, and interpretation
* Completely re-written in a contemporary style–includes user-friendly equations and more diagrams
* Covers the latest advances in the treatment of lung function, including a stronger clinical and practical bias and more on new techniques and equipment
* Keeps mathematical treatments to a minimum
Cotes’ Lung Function is an ideal guide for respiratory physicians and surgeons, staff of lung function laboratories, and others who have a professional interest in the function of the lungs at rest or on exercise and how it may be assessed. Physiologists, anthropologists, pediatricians, anesthetists, occupational physicians, explorers, epidemiologists, and respiratory nurses should also find the book useful.
Table of Content
Preface xxvii
Contributors xxix
Part I Introduction 1
1 How We Came to Have Lungs and How Our Understanding of Lung Function has Developed 3
Part II Foundations 21
2 Getting Started 23
3 Development and Functional Anatomy of the Respiratory System 33
Sungmi Jung and Richard Fraser
4 Body Size and Anthropometric Measurements 45
5 Numerical Interpretation of Physiological Variables 57
J. Martin Bland
6 Basic Terminology and Gas Laws 75
Adrian Kendrick
7 Basic Equipment and Measurement Techniques 91
Brendan G. Cooper
8 Respiratory Surveys 117
Peter G.J. Burney
9 The Application of Analytical Technique Applied to Expired Air as a Means of Monitoring Airway and Lung Function 129
Paolo Paredi and Peter Barnes
Part III Physiology and Measurement of Lung Function 149
10 Chest Wall and Respiratory Muscles 151
Andre De Troyer and John Moxham
11 Lung Volumes 177
12 Lung and Chest Wall Elasticity 187
G. John Gibson
13 Forced Ventilatory Volumes and Flows 203
Riccardo Pellegrino
14 Theory and Measurement of Respiratory Resistance 217
Jason H.T. Bates
15 The Control of Airway Function and the Assessment of Airway Calibre 231
Eric Derom
16 Ventilation, Blood Flow, and Their Inter-Relationships 259
G. Kim Prisk
17 Transfer of Gases into the Blood of Alveolar Capillaries 301
Eric Derom and Guy F. Joos
18 Transfer Factor (Tl) for carbon monoxide (CO) and nitric oxide (NO) 313
Colin D.R. Borland and Mike Hughes
19 Oxygen 353
Dan S. Karbing and Stephen E. Rees
20 Carbon Dioxide 377
Erik R. Swenson
21 Control of Respiration 389
Bertien M.-A. Buyse
22 The Sensation of Breathing 407
Mathias Schroijen, Paul W. Davenport, Omer Van den Bergh, and Ilse Van Diest
23 Breathing Function in Newborn Babies 423
Urs P. Frey and Philipp Latzin
Part IV Normal Variation in Lung Function 435
24 Normal Lung Function from Childhood to Old Age 437
Andrew Bush and Michael D.L. Morgan
25 Reference Values for Lung Function in White Children and Adults 463
26 Reference Values for Lung Function in Non-White Adults and Children 499
Part V Exercise 517
27 Physiology of Exercise and Effects of Lung Disease on Performance 519
28 Exercise Testing and Interpretation, Including Reference Values 553
29 Assessment of Exercise Limitation, Disability, and Residual Ability 577
30 Exercise in Children 587
Andrew Bush
Part VI Breathing During Sleep 595
31 Breathing During Sleep and its Investigation 597
Joerg Steier
Part VII Potentially Adverse Environments 615
32 Hypobaria 617
James Milledge
33 Immersion in Water, Hyperbaria, and Hyperoxia Including Oxygen Therapy 639
Einar Thorsen
34 Effects of Cold and Heat on the Lung 653
Malcolm Sue-Chu
Part VIII Lung Function in Clinical Practice 661
35 Strategies for Assessment of Lung Function 663
James Hull
36 Patterns of Abnormal Lung Function in Lung Disease 673
William Kinnear
37 Lung Function in Asthma, Chronic Obstructive Pulmonary Disease, and Lung Fibrosis 681
Wim Janssens and Pascal Van Bleyenbergh
38 Lung Function in Specific Respiratory and Systemic Diseases 697
Stephen J. Bourke
39 Pulmonary Rehabilitation 729
Sally Singh
40 Lung Function in Relation to Surgery, Anaesthesia, and Intensive Care 737
Goran Hedenstierna
Index 751
About the author
John Cotes, Ph D, (deceased), was a respiratory physiologist who played a key role in the conquest of Everest in 1953. He also played prominent roles in the European Respiratory Society, the Thoracic Society, and the Association of Respiratory Technicians and Physiologists, and was an honorary fellow of the Faculty of Occupational Medicine.
Robert L. Maynard, CBE, FRCP, FRCPath, is an Honorary Professor of Environmental Medicine at the University of Birmingham, Birmingham, UK.
Sarah J. Pearce, FRCP, is Formerly Consultant Physician at County Durham and Darlington NHS Foundation Trust, Darlington, UK.
Benoit B. Nemery, MD, Ph D, is Professor of Toxicology & Occupational Medicine for the Faculty of Medicine at the Department of Public Health and Primary Care, KU Leuven, Belgium.
Peter D. Wagner, MD, is Distinguished Professor of Medicine & Bioengineering at the University of California, San Diego, CA, USA.
Brendan G. Cooper, Ph D, FERS, FRSB, is Consultant Clinical Scientist in Respiratory and Sleep Physiology at University Hospital Birmingham and holds an Honorary Professorship in Respiratory & Sleep Physiology at the University of Birmingham, Birmingham, UK.
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