Stefan Jentsch & Bernhard Haendler 
The Ubiquitin System in Health and Disease [PDF ebook] 

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Table of Content

Crosstalk Between the SUMO and Ubiquitin Pathways.- A Tale of Two Giant Proteases.- Molecular Genetics of the Ubiquitin-Proteasome System: Lessons from Yeast.- Less Is More: How Protein Degradation Regulates Muscle Development.- Transcriptional Control and the Ubiquitin–Proteasome System.- Ubiquitination of Myc: Proteasomal Degradation and Beyond.- Regulation of Apoptosis and Cytokinesis by the Anti-apoptotic E2/E3 Ubiquitin-Ligase BRUCE.- Dissecting Roles of Ubiquitination in the p53 Pathway.- Regulation of T Cell Differentiation and Allergic Responses by the E3 Ubiquitin Ligase Itch.- Approaches to Discovering Drugs that Regulate E3 Ubiquitin Ligases.- Inhibiting Hdm2 and Ubiquitin-Activating Enzyme: Targeting the Ubiquitin Conjugating System in Cancer.

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Language English ● Format PDF ● Pages 191 ● ISBN 9783540851073 ● File size 2.4 MB ● Editor Stefan Jentsch & Bernhard Haendler ● Publisher Springer Berlin ● City Heidelberg ● Country DE ● Published 2008 ● Downloadable 24 months ● Currency EUR ● ID 2164394 ● Copy protection Social DRM

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